Evidence map›Paper›PMID 36028239›Full record

ArticleBMJ case reports2022

Paediatric inflammatory multisystem syndrome: temporally associated with SARS-CoV-2 (PIMS-TS) - A mimic of intra-abdominal malignancy.

Omar Nasher, Amand Friend, Bhanumathi Lakshminarayanan, Kerry Turner, Mark Wood, Antigoni Deri, Danielle Ingham

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Omar NasherPaediatric Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Amand FriendPaediatric Oncology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Bhanumathi LakshminarayananPaediatric Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Kerry TurnerCellular Pathology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Mark WoodPaediatric Rheumatology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Antigoni DeriPaediatric Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Danielle InghamPaediatric Oncology, Leeds Teaching Hospitals NHS Trust, Leeds, UK danielle.ingham@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a school-aged boy who presented with clinical features suggesting acute appendicitis. However, further imaging which included CT, demonstrated an inflammatory mass involving the transverse colon raising the suspicion of lymphoma. He then developed intestinal obstruction, and in view of the rapid progression of the disease, he was thought to have non-Hodgkin's lymphoma. He underwent an open excisional biopsy, which revealed a necroinflammatory process and no suggestion of lymphoma or an alternative malignancy or specific diagnosis. His steroid treatment was stopped, and he made a good recovery postoperatively. Positive COVID-19 antibodies, positive response to steroids, results and clinical features were consistent with paediatric inflammatory multisystem syndrome (PIMS-TS), with extensive investigation not offering an alternative diagnosis.While PIMS-TS is a relatively new entity, we believe that this case highlights the importance of it being considered a differential diagnosis of a child presenting with an inflammatory mass.

Indexed as

Abdominal NeoplasmsCOVID-19ChildHumansMaleSARS-CoV-2Systemic Inflammatory Response SyndromeCOVID-19GastroenterologyPaediatric oncologyPaediatric SurgeryPathology

Identifiers

PMID36028239
PMCPMC9422851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.