Evidence map›Paper›PMID 36028238›Full record

ArticleBMJ case reports2022

Reactivation of adult-onset Still's disease after use of the COVID-19 ChAdOx1-S vaccine.

Sebastián E Ibáñez Vodnizza, Luis Morales Murillo, Matías de la Rivera Vergara, Roberto Saldías Martínez

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sebastián E Ibáñez VodnizzaRheumatology, Facultad de medicina Clínica Alemana de Santiago - Universidad del Desarrollo, Las Condes, Región Metropolitana, Chile sibanez@alemana.cl.ORCID http://orcid.org/0000-0002-9577-3078
Luis Morales MurilloCardiology, Facultad de medicina Clínica Alemana de Santiago - Universidad del Desarrollo, Las Condes, Región Metropolitana, Chile.
Matías de la Rivera VergaraInternal Medicine, Facultad de medicina Clínica Alemana de Santiago - Universidad del Desarrollo, Las Condes, Región Metropolitana, Chile.
Roberto Saldías MartínezInternal Medicine, Facultad de medicina Clínica Alemana de Santiago - Universidad del Desarrollo, Las Condes, Región Metropolitana, Chile.
Universidad del Desarrollo · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A woman in her 60s with a history of adult-onset Still's disease (AOSD) in remission for 14 years received the ChAdOx1-S vaccine as a booster to her initial vaccination schedule (two doses of CoronaVac vaccine 6 months apart). Two weeks later, she consulted for symptoms suggestive of AOSD reactivation. This was confirmed during hospitalisation, where renal and cardiac involvement were also observed. Despite using high-dose corticosteroids, troponin T and N-terminal pro hormone B-type natriuretic peptide (NT-proBNP) were persistently elevated. Tocilizumab was used, with which the patient achieved complete remission of her symptoms and normalised her laboratory tests.

Indexed as

COVID-19Still's Disease, Adult-OnsetAdrenal Cortex HormonesChAdOx1 nCoV-19COVID-19 VaccinesFemaleHumansMiddle AgedRemission InductionAdrenal Cortex HormonesChAdOx1 nCoV-19COVID-19 VaccinesConnective tissue diseaseCOVID-19

Identifiers

PMID36028238
PMCPMC9422839
OpenAlexW4293124504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.