ReviewAnnual review of pharmacology and toxicology2023
Air Pollution-Related Neurotoxicity Across the Life Span.
Review in Annual review of pharmacology and toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Environmental epigenetic modifiers in neurodegenerative diseases: a systematic review of epigenomic mechanisms and therapeutic targets.Frontiers in epigenetics and epigenomics · 2026Pooled it
- A systematic review of air pollution exposure and brain structure and function during development.Environmental research · 2025Pooled it
- Maternal prenatal co-exposure to air pollution and psychological distress shapes the neonatal gut: microbiota-mediated pathways to early neurodevelopment.Gut microbes · 2026Article
- Induction of ferroptotic and amyloidogenic signatures linked to Alzheimer's disease by chemically distinct air pollutants.Redox biology · 2026Article
- PMiScience · 2026Review
- Within- and between-study site variations in ambient air pollution exposure at ages 9-10 years in the Adolescent Brain Cognitive Development (ABCD) Study.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Acute wood smoke exposure is associated with cell-specific hippocampal transcriptomic responses in an accelerated ovarian failure mouse model.Neurotoxicology · 2026Article
- A comprehensive overview of the biological foundations of ADHD.Bioscience reports · 2026Review
- Ambient pollution components and sources are associated with hippocampal architecture and memory in pre-adolescents.BMC medicine · 2026Article
- Impact of prenatal exposure to airborne particulate matter on local functional connections in the cerebral cortex of neonates.NeuroImage · 2026Article
- Accelerated biological aging and brain structural alterations linking air pollution to dementia risk: a prospective cohort study.The journal of nutrition, health & aging · 2026Article
- Short-term effect of PMScientific reports · 2026Article
- Neurobiophilia.Brain sciences · 2026Review
- Phthalates Induced Neurotoxicity: A Mechanistic Approach.Central nervous system agents in medicinal chemistry · 2026Review
- Air pollution decreases postsynaptic PSD-95 and NMDA receptor subunits in synaptosomes from mouse cerebral cortex.Environmental pollution (Barking, Essex : 1987) · 2025Article
- Unraveling the impact of prenatal air pollution for neonatal brain maturation.Environment international · 2025Article
- The Impact of Early Life Exposure to Air Pollution on the Brain: A Diffusion MRI Study in 10-13-Year-Old Children With and Without ADHD Diagnosis.Human brain mapping · 2025Article
- Sources and components of fine air pollution exposure and brain morphology in preadolescents.The Science of the total environment · 2025Article
- Air pollution and fetal brain morphological development: a prospective cohort study.The Lancet. Planetary health · 2025Article
- Estimating PMToxics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Air pollution is a complex mixture of gases and particulate matter, with adsorbed organic and inorganic contaminants, to which exposure is lifelong. Epidemiological studies increasingly associate air pollution with multiple neurodevelopmental disorders and neurodegenerative diseases, findings supported by experimental animal models. This breadth of neurotoxicity across these central nervous system diseases and disorders likely reflects shared vulnerability of their inflammatory and oxidative stress-based mechanisms and a corresponding ability to produce brain metal dyshomeo-stasis. Future research to define the responsible contaminants of air pollution underlying this neurotoxicity is critical to understanding mechanisms of these diseases and disorders and protecting public health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.