Observational studyClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2023
Clinical characteristics of ambulatory and hospitalized patients with monkeypox virus infection: an observational cohort study.
Observational study in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 9 of them syntheses that pooled it.
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Who cites it
100 citing papers in PubMed, 9 syntheses or guidelines pooled it, 187 citations in OpenAlex.
- Prevalence of mpox infection among men who have sex with men: a systematic review and meta-analysis.Infectious diseases of poverty · 2026Pooled it
- Hospitalization rate and patterns of clinical reasons among Mpox-confirmed cases: a systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Atypical mucocutaneous manifestations of MPOX: A systematic review.The Journal of dermatology · 2025Pooled it
- Decoding mpox: a systematic review and meta-analysis of the transmission and severity parameters of the 2022-2023 global outbreak.BMJ global health · 2025Pooled it
- A global systematic evidence review with meta-analysis of the epidemiological characteristics of the 2022 Mpox outbreaks.Infection · 2024Pooled it
- Mpox gastrointestinal manifestations: a systematic review.BMJ open gastroenterology · 2024Pooled it
- Viral Loads in Skin Samples of Patients with Monkeypox Virus Infection: A Systematic Review and Meta-Analysis.Viruses · 2023Pooled it
- The use of antivirals in the treatment of human monkeypox outbreaks: a systematic review.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023Pooled it
- Prevalence of mpox viral DNA in cutaneous specimens of monkeypox-infected patients: a systematic review and meta-analysis.Frontiers in cellular and infection microbiology · 2023Pooled it
- Mpox: clinical patterns and implications for epidemic management - a cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Treatment of Severe Ocular Mpox with Cidofovir and Tecovirimat.Emerging infectious diseases · 2026Article
- Ocular manifestations of Clade Ib mpox in four South-Kivu health zones, Democratic Republic of the Congo.PLOS global public health · 2026Article
- From skin lesions to multi-organ involvement: Organ tropism and pathogenesis of mpox virus.iScience · 2025Review
- Clinical and Sociodemographic Factors Associated With Ocular Mpox in California, May 2022 to September 2023.Sexually transmitted diseases · 2025Article
- From neglected to notoriety: a review of Mpox clinical features, virology, epidemiology, treatment and prevention strategies.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Review
- Public health and clinical response to an mpox outbreak in Slovenia: case study, 2022-2023.Sexually transmitted infections · 2025Observational
- Clinical and epidemiological characteristics among probable and confirmed patients with mpox in Sierra Leone reported from January to May 2025.medRxiv : the preprint server for health sciences · 2025Article
- Clinical Characterization and Outcomes of Human Clade IIb Mpox Virus Disease: A European Multicenter Mpox Observational Cohort Study (MOSAIC).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Observational
- Ocular Manifestations of Mpox and Other Poxvirus Infections: Clinical Insights and Emerging Therapeutic and Preventive Strategies.Vaccines · 2025Review
- Review
40 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
22 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesA global outbreak of monkeypox virus infections in human beings has been described since April 2022. The objectives of this study were to describe the clinical characteristics and complications of patients with a monkeypox infection.
methodsAll consecutive patients with a polymerase chain reaction (PCR)-confirmed monkeypox infection seen in a French referral centre were included.
resultsBetween 21 May and 5 July 2022, 264 patients had a PCR-confirmed monkeypox infection. Among them, 262 (262/264, 99%) were men, 245 (245/259, 95%) were men who have sex with men, and 90 (90/216, 42%) practiced chemsex in the last 3 months. Seventy-three (73/256, 29%) patients were living with human immunodeficiency virus infection, and 120 (120/169, 71%) patients were taking pre-exposure prophylaxis against human immunodeficiency virus infection. Overall, 112 (112/236, 47%) patients had contact with a confirmed monkeypox case; it was of sexual nature for 95% of the contacts (86/91). Monkeypox virus PCR was positive on the skin in 252 patients, on the oropharyngeal sample in 150 patients, and on blood in eight patients. The majority of patients presented with fever (171/253, 68%) and adenopathy (174/251, 69%). Skin lesions mostly affected the genital (135/252, 54%) and perianal (100/251, 40%) areas. Overall, 17 (17/264, 6%) patients were hospitalized; none of them were immunocompromised. Complications requiring hospitalization included cellulitis (n = 4), paronychia (n = 3), severe anal and digestive involvement (n = 4), non-cardia angina with dysphagia (n = 4), blepharitis (n = 1), and keratitis (n = 1). Surgical management was required in four patients.
conclusionThe current outbreak of monkeypox infections has specific characteristics: it occurs in the men who have sex with men community; known contact is mostly sexual; perineal and anal areas are frequently affected; and severe complications include superinfected skin lesions, paronychia, cellulitis, anal and digestive involvement, angina with dysphagia, and ocular involvement.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.