Evidence map›Paper›PMID 36018830›Full record

ArticleACS applied materials & interfaces2022

Hetero-Multivalent Targeted Liposomal Drug Delivery to Treat

Akshi Singla, Sabona B Simbassa, Bhagath Chirra, Anirudh Gairola, Marie R Southerland, Kush N Shah, Robert E Rose, Qingquan Chen, Ahmed Basharat, Jaime Baeza and 7 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Repurposing Birabresib to target Gram‑positive bacteria.npj antimicrobials and resistance · 2026
    Article
  2. Synthesis of α,ε-International journal of molecular sciences · 2025
    Article
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Akshi SinglaDepartment of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0002-2139-7954
Sabona B SimbassaDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.ORCID 0000-0002-5467-9739
Bhagath ChirraDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.
Anirudh GairolaDepartment of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0002-0053-9239
Marie R SoutherlandDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.
Kush N ShahDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.
Robert E RoseComparative Medicine Program, Texas A&M University, College Station, Texas 77843, United States.
Qingquan ChenDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.
Ahmed BasharatDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.
Jaime BaezaDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.
Rohit RainaDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.
Morgan J ChapmanDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.
Adel M HassanDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.
Ivan IvanovDepartment of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas 77843, United States.
Anindito SenMicroscopy and Imaging Center, Texas A&M University, College Station, Texas 77843, United States.
Hung-Jen WuDepartment of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0003-3082-7431
Carolyn L CannonDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan Texas 77807, United States.ORCID 0000-0002-2491-0389
Texas A&M Health Science Center · USTexas A&M University · USImaging Center · US

Funding

Design of hetero-multivalent targeted liposome for combating intracellular Mycobacterium tuberculosisR21AI149383 · NIAID · TEXAS ENGINEERING EXPERIMENT STATION · PI CIRILLO, JEFFREY D., WU, HUNG-JEN · 2020 to 2021
$416k
Study the interaction between Lipopolysaccharide-Binding Protein and Immune Cell MembranesR03AI139650 · NIAID · TEXAS ENGINEERING EXPERIMENT STATION · PI JAYARAMAN, ARUL, WU, HUNG-JEN · 2019 to 2020
$149k
NIAID NIH HHS R03 AI139650NIAID NIH HHS R21 AI149383
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Infective AgentsPseudomonas InfectionsAnimalsAnti-Bacterial AgentsCiprofloxacinLiposomesMiceMicrobial Sensitivity TestsPseudomonas aeruginosaAnti-Bacterial AgentsAnti-Infective AgentsCiprofloxacinLiposomesciprofloxacindrug deliveryPseudomonas aeruginosatargeted liposomesthigh infection model

Identifiers

PMID36018830
PMCPMC9480101
OpenAlexW4293155521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.