Evidence map›Paper›PMID 36018421›Full record

ArticleObesity surgery2022

Nutritional Deficiencies 3 Years After Sleeve Gastrectomy Can Be Limited by a Specialized Multivitamin Supplement.

Laura Heusschen, Agnes A M Berendsen, Laura N Deden, Eric J Hazebroek, Edo O Aarts

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Obesity surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06664580 (Enhancing Nutritional Health and Patient Satisfaction Five Years After Metabolic Bariatric Surgery with Targeted Supplementation), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06664580 completednot on this map

Enhancing Nutritional Health and Patient Satisfaction Five Years After Metabolic Bariatric Surgery with Targeted Supplementation

TypeobservationalSponsorSan Raffaele Telematic UniversityRan2017 to 2024Enrolled249ConditionsObesity and Overweight, Nutritional Deficiency, Bariatric SurgeryArmsMetabolic Bariatric Surgery Procedures
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Observational
  5. Observational
  6. Article
  7. Precision nutrition in the context of bariatric surgery.Reviews in endocrine & metabolic disorders · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laura HeusschenDepartment of Bariatric Surgery, Vitalys Part of Rijnstate Hospital, 6815 AD, Arnhem, The Netherlands. LHeusschen@Rijnstate.nl.ORCID 0000-0002-8096-0188
Agnes A M BerendsenDivison of Human Nutrition and Health, Wageningen University, 6708 WE, Wageningen, The Netherlands.
Laura N DedenDepartment of Bariatric Surgery, Vitalys Part of Rijnstate Hospital, 6815 AD, Arnhem, The Netherlands.
Eric J HazebroekDepartment of Bariatric Surgery, Vitalys Part of Rijnstate Hospital, 6815 AD, Arnhem, The Netherlands.
Edo O AartsDepartment of Bariatric Surgery, Vitalys Part of Rijnstate Hospital, 6815 AD, Arnhem, The Netherlands.
Rijnstate Hospital · NLWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLifelong daily multivitamin supplementation is highly recommended after sleeve gastrectomy (SG). Based on previous research, a specialized multivitamin supplement (MVS) for SG patients was developed and optimized (WLS Optimum 1.0 and 2.0). This study presents its mid-term effectives and compares micronutrient status of SG patients using this specialized MVS to users of standard MVS (sMVS) and non-users of multivitamin supplementation during the first three years post-surgery. MATERIALS AND

methodsOf the 226 participants that were included at baseline, yearly follow-up blood tests were completed by 193 participants (85%) at 12 months, 176 participants (78%) at 24 months, and 140 participants (62%) at 36 months of follow-up. At each time point, participants were divided into four groups: (1) Optimum 1.0, (2) Optimum 2.0, (3) sMVS, and (4) non-users. Serum concentrations (linear mixed-effects models) and the prevalence of micronutrient deficiencies (chi-square tests) during follow-up were compared between the groups.

resultsUsers of specialized MVS (Optimum 1.0 and 2.0) had higher serum concentrations of hemoglobin, folic acid, and vitamin D compared to sMVS users and non-users during follow-up. Serum concentrations of vitamin B12 and (corrected) calcium were also higher in specialized MVS users than in non-users. Overall, fewer deficiencies for folic acid and vitamin D were observed in the Optimum groups.

conclusionAlthough the perfect multivitamin supplement for all SG patients does not exist, WLS Optimum was more effective in sustaining normal serum concentrations than standard, over-the-counter supplementation. Non-users of MVS presented with most micronutrient deficiencies and will evidently develop poor nutritional status on the longer term.

Indexed as

MalnutritionObesity, MorbidDietary SupplementsFolic AcidGastrectomyHumansMicronutrientsVitamin DVitaminsFolic AcidMicronutrientsVitamin DVitaminsBariatric SurgeryDeficienciesMetabolic SurgeryMicronutrientsMineralsSGSleeve GastrectomySupplementationVitamins

Identifiers

PMID36018421
PMCPMC9613574
OpenAlexW4293168573

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.