ArticleJournal of anesthesia2022
Equilibration rate constant, k
Article in Journal of anesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recommendation for the practice of total intravenous anesthesia.Journal of anesthesia · 2024Guideline
- Predicted effect-site concentrations of remimazolam for i-gel insertion: a prospective randomized controlled study.Journal of clinical monitoring and computing · 2024Trial
- Pharmacological profiles and mechanism of action of remimazolam for ICU sedation.Journal of intensive care · 2026Review
- General anesthesia/general anesthetics: Journal of Anesthesia symposium 2025.Journal of anesthesia · 2026Article
- Relationship between effect site concentration of remimazolam at loss of consciousness and time to extubation: a prospective, single-centre, observational study.Journal of clinical monitoring and computing · 2025Observational
- Clinical Pharmacokinetics and Pharmacodynamics of Remimazolam.Clinical pharmacokinetics · 2025Review
- Development and analysis of a remimazolam pharmacokinetics and pharmacodynamics model with proposed dosing and concentrations for anaesthesia and sedation.British journal of anaesthesia · 2025Article
- The dose of remimazolam combined with sufentanil for the induction of general anesthesia in obese patients undergoing bariatric surgery: an up-and-down sequential allocation trial.Frontiers in pharmacology · 2024Article
- Efficacy and safety of remimazolam besilate for sedation in outpatients undergoing impacted third molar extraction: a prospective exploratory study.BMC oral health · 2023Article
- Article
- Total intravenous anesthesia management with simultaneous use of remimazolam and propofol: A case series of three patients.SAGE open medical case reports · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effect-site concentration is widely used to determine drug dosage in anesthesia practice. To obtain effect-site concentration, a pharmacokinetic model with a corresponding equilibration rate constant between plasma and effect-site, k
Indexed as
Identifiers
36018387What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.