Evidence map›Paper›PMID 36018345›Full record

ArticleJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2024

A novel machine learning model for class III surgery decision.

Hunter Lee, Sunna Ahmad, Michael Frazier, Mehmet Murat Dundar, Hakan Turkkahraman

Abstract read
In one paragraph

Article in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hunter LeeDepartment of Orthodontics and Oral Facial Genetics, Indiana University School of Dentistry, 1121 West Michigan Street, 46202, Indianapolis, IN, USA.
Sunna AhmadIndiana University School of Dentistry, Indianapolis, IN, USA.
Michael FrazierDepartment of Orthodontics and Oral Facial Genetics, Indiana University School of Dentistry, 1121 West Michigan Street, 46202, Indianapolis, IN, USA.
Mehmet Murat DundarDepartment of Computer and Information Science, School of Science, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA.
Hakan TurkkahramanDepartment of Orthodontics and Oral Facial Genetics, Indiana University School of Dentistry, 1121 West Michigan Street, 46202, Indianapolis, IN, USA. haturk@iu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe primary purpose of this study was to develop a new machine learning model for the surgery/non-surgery decision in class III patients and evaluate the validity and reliability of this model.

methodsThe sample consisted of 196 skeletal class III patients. All the cases were allocated randomly, 136 to the training set and the remaining 60 to the test set. Using the test set, the success rate of the artificial neural network model was estimated, along with a 95% confidence interval. To predict surgical cases, we trained a binary classifier using two different methods: random forest (RF) and logistic regression (LR).

resultsBoth the RF and the LR model showed high separability when classifying each patient for surgical or non-surgical treatment. RF achieved an area under the curve (AUC) of 0.9395 on the test set. 95% confidence intervals were computed by bootstrap sampling as lower bound = 0.7908 and higher bound = 0.9799. On the other hand, LR achieved an AUC of 0.937 on the test set. 95% confidence intervals were computed by bootstrap sampling as lower bound = 0.8467 and higher bound = 0.9812.

conclusionsRF and LR machine learning models can be used to generate accurate and reliable algorithms to successfully classify patients up to 90%. The features selected by the algorithms coincide with the clinical features that we as clinicians weigh heavily when determining a treatment plan. This study further supports that overjet, Wits appraisal, lower incisor angulation, and Holdaway H angle can be used as strong predictors in assessing a patient's surgical needs.

Indexed as

Machine LearningAdolescentFemaleHumansMaleNeural Networks, ComputerOrthognathic Surgical ProceduresReproducibility of ResultsSensitivity and SpecificityArtificial intelligenceComputer-assisted decision makingDentofacial deformitiesLogistic modelsOrthognathic surgery

Identifiers

PMID36018345
PMCPMC11186927

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.