ArticleLupus2022
The association of lupus nephritis with adverse pregnancy outcomes among women with lupus in North America.
Article in Lupus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- In Vitro Fertilization is Essential Healthcare for Patients With Rheumatic Disease.ACR open rheumatology · 2026Review
- Characterizing Perinatal Treatment Patterns and Outcomes in Myasthenia Gravis.Muscle & nerve · 2026Article
- Article
- Second Trimester Kidney Function and Adverse Pregnancy Outcomes among Patients with Lupus.Kidney360 · 2025Article
- The Impact of Pregnancy Readiness on Lupus Activity, Maternal Mental Health, and Pregnancy Outcomes.Arthritis care & research · 2024Article
- Pregnancy in Glomerular Disease: From Risk Identification to Counseling and Management.Journal of clinical medicine · 2024Review
- Effect of remission, clinical remission with active serology, and glucocorticoid dosage on the pregnancy outcome of pregnant patients with systemic lupus erythematosus.Arthritis research & therapy · 2024Article
- Implications of the accuracy of diagnostic algorithms for systemic lupus on our understanding of racial disparities in pregnancy outcomes.Rheumatology (Oxford, England) · 2024Article
- A retrospective analysis of the safety of tacrolimus use and its optimal cut-off concentration during pregnancy in women with systemic lupus erythematosus: study from two Japanese tertiary referral centers.Arthritis research & therapy · 2024Article
- Therapeutic changes of systemic lupus erythematosus (SLE) patients in pregnancy and feto-maternal outcomes: a retrospective cohort study.The Journal of international medical research · 2024Article
- Adverse Impact of Systemic Lupus Erythematosus on Pregnancy Outcomes: A Saudi Arabia Retrospective Multi-Center Study.Open access rheumatology : research and reviews · 2024Article
- Pregnancy Outcomes of Women Veterans with Autoimmune Disease.Women's health reports (New Rochelle, N.Y.) · 2024Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesWe evaluated the association of lupus nephritis (LN) and adverse pregnancy outcomes in prospective cohorts of pregnant women with SLE (systemic lupus erythematosus).
methodsWe conducted a patient-level pooled analysis of data from three cohorts of pregnant women with SLE. Pooled logistic regression models were used to evaluate the association of LN and adverse pregnancy outcomes. Odds ratios and 95% confidence intervals were calculated using a fixed effect model by enrolling cohort.
resultsThe pooled cohort included 393 women who received care at clinics in the United States and Canada from 1995 to 2015. There were 144 (37%) women with a history of LN. Compared to women without LN, those with LN had higher odds of fetal loss (OR: 1.90; 95% CI: 1.01, 3.56) and preeclampsia (OR: 2.04; 95% CI: 1.01, 4.13). Among the 31 women with active nephritis (defined as urine protein ≥ 0.5 g/24 h) there was a higher odds of poor pregnancy outcome (OR: 3.08; 95% CI: 1.31, 7.23) and fetal loss (OR: 6.29; 95% CI: 2.52, 15.70) compared to women without LN.
conclusionsIn this pooled cohort of women with SLE, a history of LN was associated with fetal loss and preeclampsia. Active nephritis was associated with poor pregnancy outcome and fetal loss.
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