ReviewFrontiers in bioengineering and biotechnology2022
Modified Mineral Trioxide Aggregate-A Versatile Dental Material: An Insight on Applications and Newer Advancements.
Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical and radiographic outcomes of pulpotomy materials in permanent teeth: a systematic review of calcium hydroxide, MTA, biodentine, and iRoot BP plus.BMC oral health · 2025Pooled it
- Pooled it
- Clinical and radiographic comparison of primary molar pulpotomy using formocresol, portland cement, and NeoMTA plus: a randomized controlled clinical trial.Scientific reports · 2024Trial
- MTA-NPs induce preferential cytotoxicity, oxidative DNA damage, and mitochondrial apoptosis in human Hep-G2 hepatocellular carcinoma cells.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Development of a Nano-Hybrid Composite Using Bovine Hydroxyapatite and Montmorillonite for Endodontic Applications-An In Vitro Study.International endodontic journal · 2026Article
- Effect of n-Butyl Cyanoacrylate Coating on the Microhardness of MM-MTA After Exposure to Moisture and Human Blood.Journal of functional biomaterials · 2026Article
- Trends and Future Perspectives in Additive Modifications of Calcium Silicate-Based Cements: A Scoping Review (2015-2024).Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- Bacterial cellulose-enhanced MTA versus conventional MTA for indirect pulp capping in primary teeth: a randomized controlled clinical trial.The Saudi dental journal · 2026Article
- Synergistic effects of collagen membrane and mineral trioxide aggregate on odontogenic differentiation and mineralization of human dental pulp stem cells: an in vitro study.BMC oral health · 2026Article
- Evaluation of the Effect of Adding Various Polymeric Rheological Agents on the Physical and Mechanical Properties of Calcium Silicate Cement.International journal of dentistry · 2026Article
- Outcome of an Extensive Mid-Root Perforation With Unintentional Bioceramic Extrusion: A Case Report With 2-Year Recall Using CBCT.Case reports in dentistry · 2026Article
- Comparative evaluation of NeoPUTTY and mineral trioxide aggregate for full pulpotomy in mature permanent molars with irreversible pulpitis: a randomized clinical study.Biomaterial investigations in dentistry · 2026Article
- Developing anti-inflammatory mineral trioxide aggregate as dental implant crown cement to reduce peri-implantitis incidence.Journal of dental sciences · 2026Article
- Evaluation of the effects of diabetes on tooth radiodensity, bond strength of root canal sealers to dentin, and interfacial elemental distribution.BMC oral health · 2025Article
- The synergistic effect of low-intensity focused ultrasound and tideglusib on odontogenic differentiation of human dental pulp stem cells.Clinical oral investigations · 2025Article
- Apical Surgery of a Maxillary Left Central Tooth Using NeoPutty After Retreatment Failure: A Case Report.Clinical case reports · 2025Article
- Irisin-Loaded Cerium-Containing Mesoporous Bioactive Glass for Effective Immunomodulation and Odontogenesis of Dental Pulp Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Management of Immature Permanent Mandibular First Molar Using NeoPutty: A Case Report.Clinical case reports · 2025Article
- Evaluation of biocompatibility, antimicrobial activity, and immunomodulatory effects of mineral trioxide aggregate modified with zeolite-clinoptilolite as a root-end filling material.BMC oral health · 2025Article
- Comparison of Two New Calcium Silicate-based Cements in Indirect Pulp Therapy in Primary Molar Teeth: Clinical Evaluative Study.International journal of clinical pediatric dentistry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mineral Trioxide Aggregate (MTA) has been a material of revolution in the field of dentistry since its introduction in the 1990s. It is being extensively used for perforation repairs, apexification, root-end filling, obturation, tooth fracture repair, regenerative procedures, apexogenesis, pulpotomies, and as a pulp-capping material because of its desired features such as biocompatibility, bioactivity, hydrophilicity, sealing ability, and low solubility. Even though its application is wide, it has its own drawbacks that prevent it from reaching its full potential as a comprehensive replacement material, including a long setting time, discoloration, mud-like consistency, and poor handling characteristics. MTA is a material of research interest currently, and many ongoing studies are still in process. In this review, the newer advancements of this versatile material by modification of its physical, chemical, and biological properties, such as change in its setting time, addressing the discoloration issue, inclusion of antimicrobial property, improved strength, regenerative ability, and biocompatibility will be discussed. Hence, it is important to have knowledge of the traditional and newer advancements of MTA to fulfill the shortcomings associated with the material.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.