Evidence map›Paper›PMID 36017340›Full record

ArticleFrontiers in physiology2022

Molecular and morphological investigations on the renal mechanisms enabling euryhalinity of red stingray

Naotaka Aburatani, Wataru Takagi, Marty Kwok-Shing Wong, Shigehiro Kuraku, Chiharu Tanegashima, Mitsutaka Kadota, Kazuhiro Saito, Waichiro Godo, Tatsuya Sakamoto, Susumu Hyodo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Sharks and rays have the oldest vertebrate sex chromosome with unique sex determination mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Naotaka AburataniAtmosphere and Ocean Research Institute, The University of Tokyo, Kashiwa, Japan.
Wataru TakagiAtmosphere and Ocean Research Institute, The University of Tokyo, Kashiwa, Japan.
Marty Kwok-Shing WongAtmosphere and Ocean Research Institute, The University of Tokyo, Kashiwa, Japan.
Shigehiro KurakuDepartment of Genomics and Evolutionary Biology, National Institute of Genetics, Mishima, Japan.
Chiharu TanegashimaLaboratory for Phyloinformatics, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Mitsutaka KadotaLaboratory for Phyloinformatics, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Kazuhiro SaitoUshimado Marine Institute, Faculty of Science, Okayama University, Setouchi, Japan.
Waichiro GodoUshimado Marine Institute, Faculty of Science, Okayama University, Setouchi, Japan.
Tatsuya SakamotoUshimado Marine Institute, Faculty of Science, Okayama University, Setouchi, Japan.
Susumu HyodoAtmosphere and Ocean Research Institute, The University of Tokyo, Kashiwa, Japan.
The University of Tokyo · JPOkayama University · JPRIKEN Center for Biosystems Dynamics Research · JPNational Institute of Genetics · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most cartilaginous fishes live in seawater (SW), but a few exceptional elasmobranchs (sharks and rays) are euryhaline and can acclimate to freshwater (FW) environments. The plasma of elasmobranchs is high in NaCl and urea concentrations, which constrains osmotic water loss. However, these euryhaline elasmobranchs maintain high levels of plasma NaCl and urea even when acclimating to low salinity, resulting in a strong osmotic gradient from external environment to body fluid. The kidney consequently produces a large volume of dilute urine to cope with the water influx. In the present study, we investigated the molecular mechanisms of dilute urine production in the kidney of Japanese red stingray,

Indexed as

Batoideacartilaginous fisheuryhalinityFW adaptationmembrane transporternephronosmoregulationurine

Identifiers

PMID36017340
PMCPMC9396271
OpenAlexW4292454428

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.