Evidence map›Paper›PMID 36017327›Full record

ArticleGenetics research2021

Transcriptome Profiles of the Liver in Two Cold-Exposed Sheep Breeds Revealed Different Mechanisms and Candidate Genes for Thermogenesis.

Dan Jiao, Kaixi Ji, Wenqiang Wang, Hu Liu, Jianwei Zhou, A Allan Degen, Yunsheng Zhang, Ping Zhou, Guo Yang

Open access · goldAbstract read
In one paragraph

Article in Genetics research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Dan JiaoNorthwest Institute of Ecological Environment and Resources, Chinese Academy of Science, Lanzhou 730000, China.ORCID 0000-0002-0393-0292
Kaixi JiNorthwest Institute of Ecological Environment and Resources, Chinese Academy of Science, Lanzhou 730000, China.ORCID 0000-0002-3604-5273
Wenqiang WangSchool of Life Sciences, Lanzhou University, Lanzhou 730020, China.
Hu LiuSchool of Life Sciences, Lanzhou University, Lanzhou 730020, China.
Jianwei ZhouSchool of Life Sciences, Lanzhou University, Lanzhou 730020, China.
A Allan DegenDesert Animal Adaptations and Husbandry, Wyler Department of Dryland Agriculture, Blaustein Institutes for Desert Research, Ben-Gurion University of Negev, Beer Sheva 8410500, Israel.
Yunsheng ZhangInstitute of Animal Husbandry, Xinjiang Academy of Animal Science, Urumqi 830000, Xinjiang, China.
Ping ZhouState Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi 832000, China.
Guo YangNorthwest Institute of Ecological Environment and Resources, Chinese Academy of Science, Lanzhou 730000, China.ORCID 0000-0002-1150-4349
Lanzhou University · CNNorthwest Institute of Eco-Environment and Resources · CNAnimal Science Research Institute · CNBen-Gurion University of the Negev · ILXinjiang Academy of Agricultural and Reclamation Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cold-induced thermogenesis plays an important role in the survival of lambs exposed to low air temperatures. The liver produces and mediates heat production in mammals; however, to date, little is known about the role of liver genes in cold-induced thermogenesis in lambs. In this study, the difference in the liver transcriptome between Altay and Hu ewe lambs was compared. Because of different backgrounds of the two breeds, we hypothesized that the transcriptome profiles of the liver would differ between breeds when exposed to cold. Cold-exposed Altay lambs activated 8 candidate genes (

Indexed as

Body Temperature RegulationTranscriptomeAnimalsCold TemperatureFemaleLiverMammalsSheepThermogenesis

Identifiers

PMID36017327
PMCPMC9364924
OpenAlexW3192625430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.