ArticleFrontiers in endocrinology2022
Impact of dyslipidemia on the cumulative pregnancy outcomes after first ovarian stimulation.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 18 citations in OpenAlex.
- The Association of Female and Male Preconception Dyslipidemia With Live Birth in Couples Seeking Fertility Treatment.The Journal of clinical endocrinology and metabolism · 2024Trial
- Gestational lipid profile partially mediates adverse obstetric outcomes associated with polycystic ovary syndrome: a multicentre cohort study in China.Lipids in health and disease · 2026Observational
- A retrospective study of the relationship between low-density lipoprotein cholesterol and pregnancy outcomes after assisted reproductive technology treatments in women with diabetes mellitus and infertility.AJOG global reports · 2026Article
- Observational
- ApoB and LDL partially explain the association between family history of diabetes and lower clinical pregnancy in women who conceived with PCOS.Frontiers in nutrition · 2026Article
- Associations of lipid metabolic parameters with cumulative live birth rate in PCOS patients undergoing IVF/ICSI and development of a nomogram-based predictive model.Frontiers in endocrinology · 2026Article
- Unraveling the Complexity of Polycystic Ovary Syndrome: Biomarkers for Diagnosis, Prognosis, and Treatment.Current pharmaceutical design · 2026Review
- Using proteomics and single-cell sequencing to analyze the pathogenesis of recurrent implantation failure associated with uterine natural killer cells.Archives of gynecology and obstetrics · 2025Article
- Identification of epidemiological risk factors associated with missed abortion in polycystic ovary syndrome: a retrospective analysis.BMC pregnancy and childbirth · 2025Article
- Is There An Association between Dyslipidemia and The Risk of Ovarian Hyperstimulation Syndrome in A Population of Non-Obese Polycystic Ovary Syndrome Patients? A Cross-Sectional Study.International journal of fertility & sterility · 2025Article
- Dyslipidemia and female reproductive failures: perspectives on lipid metabolism and endometrial immune dysregulation.Seminars in immunopathology · 2025Review
- Effects of high-normal fasting blood glucose on ART outcomes of frozen-thawed single blastocyst transfer in women with normal BMI.Journal of assisted reproduction and genetics · 2024Article
- Characteristics, Physiopathology and Management of Dyslipidemias in Pregnancy: A Narrative Review.Nutrients · 2024Review
- Characterization of the gut microbiota in polycystic ovary syndrome with dyslipidemia.BMC microbiology · 2024Article
- Hyperlipidemia is negatively associated with pregnancy outcomes in patients following frozen-thawed embryo transfer: A retrospective study.Health science reports · 2024Article
- Lipoprotein alterations in endocrine disorders - a review of the recent developments in the field.Frontiers in endocrinology · 2024Review
- Adiposity and lipid metabolism indicators mediate the adverse effect of glucose metabolism indicators on oogenesis and embryogenesis in PCOS women undergoing IVF/ICSI cycles.European journal of medical research · 2023Article
- Inflammation mediates the effect of adiposity and lipid metabolism indicators on the embryogenesis of PCOS women undergoingFrontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To investigate the cumulative live birth rate (CLBR) according to lipid metabolism in patients with or without polycystic ovarian syndrome (PCOS) undergoing their first complete Patients: A total of 1,470 patients with PCOS and 3,232 patients without PCOS who underwent their first complete IVF/ICSI cycles from January 2016 to June 2018 were included. During a minimum of 2 years of follow-up, they had achieved at least one live birth or used all available embryos. The cumulative pregnancy outcomes were compared based on the patients' blood lipid parameters, including triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), in the two populations. Patients with an abnormal level of one or more of these four indicators were considered the dyslipidemia group. Patients whose four indicators were normal were considered the control group. Results: Among 1,470 patients with PCOS, the cumulative pregnancy outcomes were similar in the dyslipidemia group and control group. Logistic regression analysis showed that the TC levels were significantly negatively associated with the cumulative live birth rate (CLBR) after adjustment for confounding factors such as age and BMI (aOR 0.81, 95% CI 0.66-0.98, P<0.05). Among the 3,232 patients without PCOS, there was no significant difference in the cumulative pregnancy outcomes between the dyslipidemia group and the control group. No significant correlations were found in other logistic regression analyses. Conclusions: TC negatively impacts the CLBR after first ovarian stimulation in PCOS patients. PCOS patients with dyslipidemia caused by elevated TC may have a poor CLBR.
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