Evidence map›Paper›PMID 36017115›Full record

ArticleClinical case reports2022

Prenatal overgrowth and polydramnios: Would you think about Noonan syndrome?

Benedetta Beltrami, Jacopo Cerasani, Alessandra Consales, Roberta Villa, Nicoletta Resta, Daria Carmela Loconte, Simona Boito, Luca Caschera, Laura Bassi, Lorenzo Colombo and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Benedetta BeltramiMedical Genetics Unit Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico Milan Italy.ORCID https://orcid.org/0000-0001-6304-0681
Jacopo CerasaniNeonatal Intensive Care Unit (NICU), Department of Clinical Science and Community Health Università degli Studi di Milano and Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan Italy.
Alessandra ConsalesNeonatal Intensive Care Unit (NICU), Department of Clinical Science and Community Health Università degli Studi di Milano and Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan Italy.
Roberta VillaMedical Genetics Unit Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico Milan Italy.
Nicoletta RestaDepartment of Biomedical Sciences and Human Oncology (DIMO), Medical Genetics University of Bari "Aldo Moro" Bari Italy.
Daria Carmela LoconteDepartment of Biomedical Sciences and Human Oncology (DIMO), Medical Genetics University of Bari "Aldo Moro" Bari Italy.ORCID https://orcid.org/0000-0002-4578-0165
Simona BoitoFetal Medicine and Surgery Service Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan Italy.
Luca CascheraNeuroradiology Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan Italy.
Laura BassiNeonatal Intensive Care Unit (NICU), Department of Clinical Science and Community Health Università degli Studi di Milano and Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan Italy.
Lorenzo ColomboNeonatal Intensive Care Unit (NICU), Department of Clinical Science and Community Health Università degli Studi di Milano and Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan Italy.
Maria IasconeLaboratory of Medical Genetics Ospedale Papa Giovanni XXIII Bergamo Italy.ORCID https://orcid.org/0000-0002-4707-212X
Maria Francesca BedeschiMedical Genetics Unit Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico Milan Italy.ORCID https://orcid.org/0000-0002-6723-9177
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · ITUniversity of Bari Aldo Moro · ITOspedale Papa Giovanni XXIII · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on a child with prenatal findings of increased nuchal translucency, polydramnios, ascites, and overgrowth. At birth, she presented length >97° centile, minor facial anomalies, megalencephaly, and Wolff-Parkinson-White syndrome. Whole-exome sequencing showed a pathogenic variant in the

Indexed as

cardiovascular disordersgeneticsneurologyobstetrics and gynecologypediatrics and adolescent medicine

Identifiers

PMID36017115
PMCPMC9393876
OpenAlexW4292582294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.