ArticleInternational journal of ophthalmology2022
Photopic pupil size change in myopic orthokeratology and its influence on axial length elongation.
Article in International journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Efficacy of Orthokeratology in Controlling Axial Elongation in Myopic Children and Adolescents: A Systematic Review and Meta-Analysis of Comparative Interventions.Journal of clinical medicine · 2026Review
- Photopic pupil size, foveal anatomy and emmetropisation: a cross-sectional study in adult eyes.BMJ open ophthalmology · 2026Article
- Reduced myopia progression with low-dose atropine in DIMS non-responders and evidence of altered pupillary light reflex kinetics.Scientific reports · 2026Article
- Effects of Myopia Control Spectacle Lenses on Peripheral Refraction and Contrast: Insights From Optical Modeling.Investigative ophthalmology & visual science · 2026Article
- Long-term effects of orthokeratology on moderate myopia progression in children: A 3-year prospective study.Experimental and therapeutic medicine · 2026Article
- One-year effects of orthokeratology lens wear on objective visual quality and corneal densitometry in adolescents with myopia.PloS one · 2026Article
- Experimental and modeling analysis of lenses with concentric cylindrical annular refractive elements: impact on peripheral imaging.Biomedical optics express · 2025Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo explore the photopic pupil size behavior in myopic children undergoing overnight orthokeratology (ortho-k) over 1-year period and its effects on the axial elongation.
methodsA total of 202 Chinese myopic children were enrolled in this prospective clinical trial. Ninety-five subjects in ortho-k group and eighty-eight subjects in spectacle group completed the 1-year study. Axial length (AL) was measured before enrollment and every 6mo after the start of ortho-k. The photopic pupil diameter (PPD) was determined using the Pentacam AXL and measured in an examination room with lighting of 300-310 Lx. Stepwise multiple linear regression analysis was used to identify variables contribution to axial elongation.
resultsCompared with spectacle group, the average 1-year axial elongation was significantly slower in the ortho-k group (0.25±0.27
conclusionPPDs experience significantly decreases at 1-month and 3-month ortho-k treatment. Children with smaller PPD tend to experience slower axial elongation and may benefit more from ortho-k.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.