Evidence map›Paper›PMID 36016876›Full record

SynthesisFrontiers in pediatrics2022

Mortality in children with cancer and SARS-CoV-2 in Latin America: A systematic review.

Elisa Dorantes-Acosta, Diana Ávila-Montiel, Jesús Domínguez Rojas, Patricia Parra-Nigañez, Liliana Velasco-Hidalgo, Sergio Arias, Lourdes Gutiérrez-Rivera, Luis Juárez-Villegas, Horacio Márquez-González

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elisa Dorantes-AcostaBiobanco de Investigación en Células Leucémicas, Hospital Infantil de México Federico Gómez, México City, Mexico.
Diana Ávila-MontielInvestigación Clínica, Hospital Infantil de México Federico Gómez, México City, Mexico.
Jesús Domínguez RojasUnidad de Cuidados Intensivos Pediátricos, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru.
Patricia Parra-NigañezDepartamento de Oncología Pediátrica, Hospital del Niño "Dr. Ovidio Aliaga Uria", La Paz, Bolivia.
Liliana Velasco-HidalgoDepartamento de Oncología Pediátrica del Instituto Nacional de Pediatría, Ciudad de Mexico, Mexico.
Sergio AriasDepartamento Programas de Salud, INER Emilio Coni, Epidemiología y Salud Pública, Facultad de Bioquímica y Ciencias Biológicas (FBCB), Universidad Nacional del Litoral (UNL), Santa Fe, Argentina.
Lourdes Gutiérrez-RiveraOncología Pediátrica, Centro Médico Nacional Siglo XXI, UMAE Hospital de Pediatría, Instituto Mexicano del Seguro Social (IMSS), México City, Mexico.
Luis Juárez-VillegasDepartamento de Onco-Hematología, Hospital Infantil de México Federico Gómez, México City, Mexico.
Horacio Márquez-GonzálezInvestigación Clínica, Hospital Infantil de México Federico Gómez, México City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The new COVID-19 disease is caused by a novel coronavirus (SARS-CoV-2), that probably originated in Wuhan, China, and has currently infected 505,817,953 people and caused 6,213,876 deaths in the world. On the American continent, 152,265,980 cases and 2,717,108 deaths have been reported to WHO (World Health Organization). The Latin America and the Caribbean (LAC) region presents an epidemiological challenge due to its population's heterogeneity and socioeconomic inequality. A particularly vulnerable population is that of children with cancer, and their mortality from COVID-19 has been reported to be 3.6% globally. This work aimed to study the lethality of SARS-CoV-2 infection in children with cancer in the Latin American region. Our objective was to systematically review published scientific literature and search hospital databases in Latin America to explore mortality in this region. A median of mortality of 9.8% was found in the articles analyzed. In addition, we collected five databases from Latin American hospitals. We concluded that there was an underestimation in the mortality registry of this group of patients in the analyzed region. Therefore, although the causes are unknown, it is necessary to strengthen the case-reporting system to determine the reality in complex and particular areas such as Latin America.

Indexed as

cancerchildrenCOVID-19Latin AmericapediatricSARS-CoV-2

Identifiers

PMID36016876
PMCPMC9396238

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.