ArticleComputational and structural biotechnology journal2022
Metabolomics and biochemical assays reveal the metabolic responses to hypo-salinity stress and osmoregulatory role of cAMP-PKA pathway in
Article in Computational and structural biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 53 citations in OpenAlex.
- Physiological and Immuno-Antioxidant Responses ofBiology · 2026Article
- Metabolomics identifies tissue-specific trends in butter clams (Saxidomus gigantea) across a subarctic fjord-type estuarine system.Marine environmental research · 2026Article
- Identification of the Potential Functions of theInternational journal of molecular sciences · 2026Article
- Response mechanism to heat and hypoxia stress in hard clam: insights from antioxidation and lipid metabolism.Frontiers in zoology · 2026Article
- Article
- Metabolomic and physiological insights to ameliorate post-harvest stress in cultured mussels.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Effects of the Interaction of Salinity and Rare Earth Elements on the Health ofJournal of xenobiotics · 2024Article
- Multi-tissue metabolomic profiling reveals the crucial metabolites and pathways associated with scallop growth.BMC genomics · 2024Article
- Effects of Nutrient Source, Temperature, and Salinity on the Growth and Survival of Three Giant Clam Species (Tridacnidae).Animals : an open access journal from MDPI · 2024Article
- Mechanisms of Gills Response to Cadmium Exposure in Greenfin Horse-Faced Filefish (Animals : an open access journal from MDPI · 2024Article
- Metabolomics-Based Investigation on the Metabolic Changes inMetabolites · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypo-salinity events frequently occur in marine ecosystem due to persistent rainfall and freshwater inflow, reducing the cytosol osmolarity and triggering cellular stress responses in aquatic organisms. Euryhaline bivalves have developed sophisticated regulatory mechanisms to adapt to salinity fluctuations over a long period of evolution. In this study, we performed multiple biochemical assays, widely targeted metabolomics, and gene expression analysis to investigate the comprehensive metabolic responses to hypo-salinity stress and osmoregulation mechanisms in hard clam
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.