Evidence map›Paper›PMID 36016711›Full record

ReviewComputational and structural biotechnology journal2022

Looking to the stars for answers: Strategies for determining how astrocytes influence neuronal activity.

Jacqueline E Paniccia, James M Otis, Michael D Scofield

Open access · goldAbstract readReview
In one paragraph

Review in Computational and structural biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Modeling traveling calcium waves in cellular structures.Journal of computational neuroscience · 2025
    Article
  4. Neuron-Glial Interactions: Implications for Plasticity, Behavior, and Cognition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jacqueline E PanicciaDepartment of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston, SC, United States.
James M OtisDepartment of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston, SC, United States.
Michael D ScofieldDepartment of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston, SC, United States.
Medical University of South Carolina · US

Funding

COCA: Project 4. Neurocircuit Strategy to Decrease Cocaine Cue ReactivityP50DA046373 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HANLON, COLLEEN A · 2019 to 2023
$9.9M
Nitrergic interneurons and cue-induced cocaine seekingR01DA054154 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SCOFIELD, MICHAEL DAVID · 2021 to 2025
$1.7M
NIDA NIH HHS P50 DA046373NIDA NIH HHS R01 DA054154
6 · The paper itself

Abstract

Astrocytes are critical components of neural circuits positioned in close proximity to the synapse, allowing them to rapidly sense and respond to neuronal activity. One repeatedly observed biomarker of astroglial activation is an increase in intracellular Ca

Indexed as

AstrocytesCa2+ imagingGenetic indicatorsMorphologyViral vectors

Identifiers

PMID36016711
PMCPMC9379862
OpenAlexW4289526219

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.