Evidence map›Paper›PMID 36016658›Full record

ArticleFrontiers in cell and developmental biology2022

Dyslexia associated gene

Steven Paniagua, Bilal Cakir, Yue Hu, Ferdi Ridvan Kiral, Yoshiaki Tanaka, Yangfei Xiang, Benjamin Patterson, Jeffrey R Gruen, In-Hyun Park

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Steven PaniaguaDepartment of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.
Bilal CakirDepartment of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.
Yue HuDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, United States.
Ferdi Ridvan KiralDepartment of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.
Yoshiaki TanakaDepartment of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.
Yangfei XiangSchool of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Benjamin PattersonDepartment of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.
Jeffrey R GruenDepartments of Pediatrics and of Genetics, Yale School of Medicine, New Haven, CT, United States.
In-Hyun ParkDepartment of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.
Pediatrics and Genetics · USYale Cancer Center · USCancer Research And Biostatistics · USShanghaiTech University · CN

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
VALIDITY OF SUBTYPES OF ADHDP50HD027802 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI LAUREN M McGRATH · 1990 to 2026
$44.9M
Analysis of Genomic and Complex DataR01HG010171 · NHGRI · YALE UNIVERSITY · PI ZHANG, HEPING · 2019 to 2022
$1.4M
Genes to behavior: Unlocking the code for early detection of reading disorderR15HD087937 · NICHD · LAFAYETTE COLLEGE · PI GABEL, LISA A · 2017 to 2017
$374k
NCATS NIH HHS UL1 TR001863NHGRI NIH HHS R01 HG010171NICHD NIH HHS P50 HD027802NICHD NIH HHS R15 HD087937
6 · The paper itself

Abstract

Dyslexia, also known as reading disability, is defined as difficulty processing written language in individuals with normal intellectual capacity and educational opportunity. The prevalence of dyslexia is between 5 and 17%, and the heritability ranges from 44 to 75%. Genetic linkage analysis and association studies have identified several genes and regulatory elements linked to dyslexia and reading ability. However, their functions and molecular mechanisms are not well understood. Prominent among these is

Indexed as

cell cycledifferentiationhESCsKIAA0319NPCs

Identifiers

PMID36016658
PMCPMC9395643
OpenAlexW4290738915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.