SynthesisInternational endodontic journal2022
Prevalence of root canal treatment worldwide: A systematic review and meta-analysis.
Synthesis in International endodontic journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Exploring Technological Progress in Three-Dimensional Imaging for Root Canal Treatments: A Systematic Review.International dental journal · 2025Pooled it
- Apical periodontitis in inflammatory bowel disease: a meta-analysis at patient and tooth level.Frontiers in dental medicine · 2025Pooled it
- Pooled it
- Apical periodontitis in osteoporotic postmenopausal women: Systematic review and meta-analysis.Medicina oral, patologia oral y cirugia bucal · 2024Pooled it
- Quality of Root Canal Fillings and Procedural Errors for In Vivo Studies Prepared in Different Clinical Settings and with Rotary Systems: A Systematic Review.Medical science monitor : international medical journal of experimental and clinical research · 2024Pooled it
- Prevalence of root canal treatment worldwide: A systematic review and meta-analysis.International endodontic journal · 2022Pooled it
- Non-surgical root canal treatments in a public dental service: Characteristics of patients, teeth and operators from a 16-year register-based study.Clinical oral investigations · 2026Article
- Cost-effectiveness of tooth preservation versus implant for persistent periapical pathosis in mandibular second molars.International journal of implant dentistry · 2026Article
- Root-Filled Teeth With and Without Pain in a Cohort of Individuals Scheduled for Regular Dental Check-Ups. A Matched Case-Control Study.Journal of oral rehabilitation · 2026Article
- Analgesic and Sedative Effects of Virtual Reality on Children with Acute Pulpitis: A Study Protocol for a Randomised Controlled Trial.Journal of pain research · 2026Article
- Phage mediated growth inhibition and biofilm disruption of the endodontic pathogen Enterococcus faecalis.PloS one · 2026Article
- Fracture Resistance of Endodontically Treated Teeth with Different Perforation Diameters: An In Vitro Analysis.Dentistry journal · 2026Article
- PFKFB3-Inhibitor 3PO-Mediated Glycolytic Reprogramming Promotes Inflammatory Dental Pulp Repair: An In Vitro and In Vivo Study.International endodontic journal · 2025Article
- Chronic Kidney Disease and Chronic Oral Inflammatory Diseases: A Systematic Review and Meta-Analysis of Periodontitis and Apical Periodontitis.Journal of clinical medicine · 2025Review
- Photon-counting CT outperforms dental CBCT in detecting small accessory canals in root-filled teeth in a phantom study.Scientific reports · 2025Article
- Immediate or delayed direct restoration does not significantly influence additional endodontic treatments and 5-year tooth survival of first molars.Acta odontologica Scandinavica · 2025Article
- Polydopamine@Zinc oxide coated macroporous membrane for antibacterial protection and early pulp repair in pulpitis.Materials today. Bio · 2025Article
- Epidemiology of Endodontic Treatment in Far North Queensland, Australia: A Retrospective Observational Study of 11 Years.Clinical and experimental dental research · 2025Observational
- A Retrospective Study of CBCT-Based Detection of Endodontic Failures and Periapical Lesions in a Romanian Cohort.Journal of clinical medicine · 2025Article
- Mechanistic insights into dental stem cells-derived exosomes in regenerative endodontics.International endodontic journal · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of root filled teeth (RFT) worldwide will inform about the amount of clinical activity of dentists dedicated to treat endodontic disease.
objectivesTo carry out a systematic review with meta-analysis answering the following question: What is the prevalence of RFT around the world? The percentage of people with at least one RFT was also investigated.
methodsA systematic review including population-based studies using the following databases: PubMed, EMBASE and Scielo. Studies related to prevalence of RFT were included. The outcome of interest of the study was the prevalence of RFT. The meta-analyses were calculated with the Open Meta Analyst software to determine the global prevalence of RFT. Subgroups analyses were performed comparing geographical distribution, radiographic method and year of the study (classified in 20th or 21th century). The prevalence of people with at least one RFT was also analysed.
resultsSeventy-four population-based studies fulfilled the inclusion criteria. Twenty-eight, forty-four and two studies reported high, moderate and low risk of bias, respectively. No obvious publication bias was observed. Prevalence of RFT was estimated with 1 201 255 teeth and 32 162 patients. The calculated worldwide prevalence of RFT was 8.2% (95% CI = 7.3%-9.1%; p < .001). The global prevalence of people with at least one RFT was 55.7% (95% CI = 49.6%-61.8%; p < .001). In 20th century, the prevalence of RFT was 10.2% (95% CI = 7.9%-12.5%; p < .001), whereas in the 21st century the overall calculated prevalence of RFT was 7.5% (95% CI = 6.5%-8.6%; p < .001). Brazilian people (12%) and the European population (9.3%) showed the highest prevalence of RFT. In Europe, 59.6% (95% CI = 52.4%-66.8%) of people has at least one RFT.
conclusionsThis review showed that root canal treatment is a very common therapy throughout the world. More than half of the studied population have at least one RFT. A limitation of the present study is that most of the studies did not consider random sampling for population selection. REGISTRATION: PROSPERO Systematic review registration number: (CRD42022329053).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.