Evidence map›Paper›PMID 36016335›Full record

ArticleViruses2022

Expression of NAC1 Restrains the Memory Formation of CD8

Liqing Wang, Anil Kumar, Jugal Kishore Das, Yijie Ren, Hao-Yun Peng, Darby Jane Ballard, Xiaofang Xiong, Jacob Rance Davis, Xingcong Ren, Jin-Ming Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Nucleus Accumbens Associated Protein 1 in Cancers-The Real Value.International journal of molecular sciences · 2024
    Article
  4. Article
  5. Role of T Cells in Microbial Pathogenesis.Pathogens (Basel, Switzerland) · 2023
    Article
  6. Control of CD4Signal transduction and targeted therapy · 2023
    Article
  7. Review
  8. NAC1 confines virus-specific memory formation of CD4Journal of medical virology · 2023
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Liqing WangDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.ORCID 0000-0001-8769-5148
Anil KumarDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.ORCID 0000-0002-7611-5918
Jugal Kishore DasDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.ORCID 0000-0002-4553-2196
Yijie RenDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.
Hao-Yun PengDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.
Darby Jane BallardDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.
Xiaofang XiongDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.
Jacob Rance DavisDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.ORCID 0000-0003-3633-6991
Xingcong RenDepartment of Toxicology and Cancer Biology, Department of Pharmacology and Nutritional Science, and Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
Jin-Ming YangDepartment of Toxicology and Cancer Biology, Department of Pharmacology and Nutritional Science, and Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
Jianxun SongDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.ORCID 0000-0002-9734-6176
Texas A&M Health Science Center · USUniversity of Kentucky · US

Funding

Nucleus Accumbens-Associated Protein-1 in Melanoma ImmunotherapyR01CA221867 · NCI · UNIVERSITY OF KENTUCKY · PI SONG, JIANXUN JIM, YANG, JIN-MING · 2018 to 2023
$2.8M
Stem cell-derived regulatory T cells for therapeutic use in arthritisR01AI121180 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI SONG, JIANXUN JIM · 2016 to 2020
$1.9M
Combating chronic neuroinflammatory disorders by targeting NAC1R21AI167793 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI SONG, JIANXUN JIM · 2022 to 2023
$413k
NCI NIH HHS R01 CA221867NCI NIH HHS R01CA221867NIAID NIH HHS R01 AI121180NIAID NIH HHS R21 AI167793NIH HHS R01AI121180 and R21AI167793
6 · The paper itself

Abstract

Nucleus accumbens-associated protein 1 (NAC1) is a transcription co-factor that has been shown to possess multiple roles in stem cell and cancer biology. However, little is known about its roles in regulation of the immune system. In the current study, we observed that expression of NAC1 impacted the survival of CD8

Indexed as

CD8-Positive T-LymphocytesVirus DiseasesAnimalsImmunologic MemoryMiceMice, Inbred C57BLMice, KnockoutVaccinia virusCD8+ T cell memoryIRF4NAC1vaccinia virus

Identifiers

PMID36016335
PMCPMC9414488
OpenAlexW4289860882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.