Evidence map›Paper›PMID 36016111›Full record

ReviewVaccines2022

COVID-19 Vaccine Booster Strategies for Omicron SARS-CoV-2 Variant: Effectiveness and Future Prospects.

Dorota Zarębska-Michaluk, Chenlin Hu, Michał Brzdęk, Robert Flisiak, Piotr Rzymski

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Dorota Zarębska-MichalukDepartment of Infectious Diseases, Jan Kochanowski University, 25-369 Kielce, Poland.ORCID 0000-0003-0938-1084
Chenlin HuCollege of Pharmacy, University of Houston, Houston, TX 77204, USA.
Michał BrzdękDepartment of Infectious Diseases, Jan Kochanowski University, 25-369 Kielce, Poland.ORCID 0000-0002-1180-9230
Robert FlisiakDepartment of Infectious Diseases and Hepatology, Medical University of Białystok, 15-540 Białystok, Poland.ORCID 0000-0003-3394-1635
Piotr RzymskiDepartment of Environmental Medicine, Poznan University of Medical Sciences, 60-806 Poznan, Poland.ORCID 0000-0002-4713-0801
Jan Kochanowski University · PLMedical University of Białystok · PLPoznan University of Medical Sciences · PLUniversity of Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the light of the lack of authorized COVID-19 vaccines adapted to the Omicron variant lineage, the administration of the first and second booster dose is recommended. It remains important to monitor the efficacy of such an approach in order to inform future preventive strategies. The present paper summarizes the research progress on the effectiveness of the first and second booster doses of COVID-19. It also discusses the potential approach in vaccination strategies that could be undertaken to maintain high levels of protection during the waves of SARS-CoV-2 infections. Although this approach can be based, with some shortcomings, on the first-generation vaccines, other vaccination strategies should be explored, including developing multiple antigen-based (multivariant-adapted) booster doses with enhanced durability of immune protection, e.g., through optimization of the half-life of generated antibodies.

Indexed as

boosterCOVID-19Omicronvaccine effectiveness

Identifiers

PMID36016111
PMCPMC9412973
OpenAlexW4289529342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.