Evidence map›Paper›PMID 36015227›Full record

ArticlePharmaceutics2022

A Comparative Study of Quercetin-Loaded Nanocochleates and Liposomes: Formulation, Characterization, Assessment of Degradation and In Vitro Anticancer Potential.

Neha Munot, Ujjwala Kandekar, Prabhanjan S Giram, Kavita Khot, Abhinandan Patil, Simona Cavalu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
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  3. A Review ofFoods (Basel, Switzerland) · 2026
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  4. [Formation mechanisms, construction, and performance evaluation of self-assembled nanoparticles derived from natural products].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Neha MunotDepartment of Pharmaceutics, School of Pharmacy, Vishwakarma University, Pune 411048, Maharashtra, India.ORCID 0000-0003-2867-9871
Ujjwala KandekarDepartment of Pharmaceutics, JSPMs Rajarshi Shahu College of Pharmacy and Research, Tathwade, Pune 411033, Maharashtra, India.
Prabhanjan S GiramDepartment of Pharmaceutics, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune 411018, Maharashtra, India.ORCID 0000-0003-0439-1347
Kavita KhotDepartment of Pharmaceutics, Sinhgad Technical Education Society's Smt. Kashibai Navale College of Pharmacy, Pune 411048, Maharashtra, India.
Abhinandan PatilDepartment of Pharmaceutics, School of Pharmacy, Sanjay Ghodawat University, Kolhapur 416118, Maharashtra, India.
Simona CavaluFaculty of Medicine and Pharmacy, University of Medicine, P-ta 1 Decembrie 10, 410087 Oradea, Romania.ORCID 0000-0001-7810-8925
Dr. D. Y. Patil Medical College, Hospital and Research Centre · INSanjay Ghodawat University · INSmt. Kashibai Navale Medical College and General hospital · INUniversity of Oradea · ROVishwakarma University

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetin, a flavonoid, has antioxidant and anti-inflammatory properties and the potential to inhibit the proliferation of cancer, but its therapeutic efficacy is lowered due to poor solubility and bioavailability. Quercetin-loaded nanocochleates (QN) were developed using a trapping method by the addition of calcium ions into preformed negatively charged liposomes (QL) prepared by a thin-film hydration method. Liposomes were optimized by varying the concentration of Dimyristoyl phosphatidyl glycerol and quercetin by applying D-optimal factorial design using Design-Expert

Indexed as

dimyristoyl phosphatidyl glycerolhuman mouth cancerKB cell linesliposomesnanocochleatesquercetinrat liver homogenate (S9G)

Identifiers

PMID36015227
PMCPMC9415452
OpenAlexW4289203694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.