Evidence map›Paper›PMID 36015189›Full record

ReviewPharmaceutics2022

An Overview on Immunogenic Cell Death in Cancer Biology and Therapy.

Mosar Corrêa Rodrigues, José Athayde Vasconcelos Morais, Rayane Ganassin, Giulia Rosa Tavares Oliveira, Fabiana Chagas Costa, Amanda Alencar Cabral Morais, Ariane Pandolfo Silveira, Victor Carlos Mello Silva, João Paulo Figueiró Longo, Luis Alexandre Muehlmann

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Trial
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  8. Nanovaccines for lung cancer: Platforms, mechanistic insights, and translational challenges.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mosar Corrêa RodriguesFaculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.
José Athayde Vasconcelos MoraisFaculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.ORCID 0000-0003-3067-4842
Rayane GanassinFaculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.
Giulia Rosa Tavares OliveiraFaculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.
Fabiana Chagas CostaFaculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.
Amanda Alencar Cabral MoraisLaboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil.ORCID 0000-0002-6974-0889
Ariane Pandolfo SilveiraLaboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
Victor Carlos Mello SilvaLaboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
João Paulo Figueiró LongoLaboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil.ORCID 0000-0002-5154-7263
Luis Alexandre MuehlmannFaculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Foundation for Research Support of the Federal District 00193.00001053/2021-24National Council for Scientific and Technological Development 403536/2021-9
6 · The paper itself

Abstract

Immunogenic cell death (ICD) is a modality of regulated cell death that is sufficient to promote an adaptive immune response against antigens of the dying cell in an immunocompetent host. An important characteristic of ICD is the release and exposure of damage-associated molecular patterns, which are potent endogenous immune adjuvants. As the induction of ICD can be achieved with conventional cytotoxic agents, it represents a potential approach for the immunotherapy of cancer. Here, different aspects of ICD in cancer biology and treatment are reviewed.

Indexed as

chemotherapyDAMPsimmune systemimmunotherapyphotodynamic therapyradiotherapy

Identifiers

PMID36015189
PMCPMC9413301

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.