Evidence map›Paper›PMID 36015064›Full record

ArticlePathogens (Basel, Switzerland)2022

Linear Peptide Epitopes Derived from ErpP, p35, and FlaB in the Serodiagnosis of Lyme Disease.

Paul M Arnaboldi, Adiya S Katseff, Mariya Sambir, Raymond J Dattwyler

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Borrelia surface proteins: new horizons in Lyme disease diagnosis.Applied microbiology and biotechnology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Tick-Borne Bacterial Diseases in Europe: Threats to public health.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Review
  9. Article
  10. Epitope Mapping of BmpA and BBK32ACS infectious diseases · 2023
    Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paul M ArnaboldiDepartment of Pathology, Microbiology, and Immunology, New York Medical College, Valhalla, NY 10595, USA.ORCID 0000-0002-4005-4412
Adiya S KatseffDepartment of Pathology, Microbiology, and Immunology, New York Medical College, Valhalla, NY 10595, USA.ORCID 0000-0003-1174-8957
Mariya SambirDepartment of Pathology, Microbiology, and Immunology, New York Medical College, Valhalla, NY 10595, USA.
Raymond J DattwylerDepartment of Pathology, Microbiology, and Immunology, New York Medical College, Valhalla, NY 10595, USA.ORCID 0000-0002-1983-1301
New York Medical College · US

Funding

A peptide-based point-of-care vertical flow assay for the rapid diagnosis of Lyme diseaseR44AI150060 · NIAID · BIOPEPTIDES, INC. · PI ARNABOLDI, PAUL MICHAEL, DI CARLO, DINO · 2020 to 2023
$3.3M
Development of a cytokine release assay for the diagnosis of Lyme diseaseR44AI102435 · NIAID · BIOPEPTIDES, INC. · PI ARNABOLDI, PAUL MICHAEL · 2016 to 2017
$1.2M
Development of a Cytokine Release Assay as a Diagnostic Test for Lyme DiseaseR43AI102435 · NIAID · BIOPEPTIDES, INC. · PI ARNABOLDI, PAUL MICHAEL · 2012 to 2013
$600k
Peptide-based Multiplex Assay for Lyme disease SerodiagnosisR43AI122399 · NIAID · BIOPEPTIDES, INC. · PI ARNABOLDI, PAUL MICHAEL · 2016 to 2016
$176k
A Rapid Point-of-Care Assay for the Diagnosis of Lyme DiseaseR43AI120364 · NIAID · BIOPEPTIDES, INC. · PI ARNABOLDI, PAUL MICHAEL · 2016 to 2016
$152k
National Institute of Allergy and Infectious Diseases AI102435, AI120364, and AI122399NIAID NIH HHS R43 AI102435NIAID NIH HHS R43 AI120364NIAID NIH HHS R43 AI122399NIAID NIH HHS R44 AI102435NIAID NIH HHS R44 AI150060
6 · The paper itself

Abstract

Lyme disease is the most common vector-borne disease in the northern hemisphere. Current serodiagnostics are insensitive in early infection. Sensitivity in these seroassays is compromised by the necessity to preserve specificity in the presence of cross-reactive epitopes in

Indexed as

Borrelia burgdorferilinear epitopesLyme disease

Identifiers

PMID36015064
PMCPMC9414810
OpenAlexW4292554462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.