Evidence map›Paper›PMID 36015014›Full record

ArticlePathogens (Basel, Switzerland)2022

ELISA Test Based on the Phenolic Glycolipid-I (PGL-I) of

Silvia Stefania Longoni, Anna Beltrame, Marco Prato, John Stewart Spencer, Nicolo Bergamaschi, Andrea Clapasson, Aurora Parodi, Chiara Piubelli, Francesca Perandin

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Seroprevalence ofThe Lancet regional health. Southeast Asia · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Silvia Stefania LongoniDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, 37024 Verona, Italy.ORCID 0000-0002-2447-1777
Anna BeltrameDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, 37024 Verona, Italy.
Marco PratoDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, 37024 Verona, Italy.
John Stewart SpencerMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Nicolo BergamaschiDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, 37024 Verona, Italy.
Andrea ClapassonDermatological Clinic, National Reference Center for Hansen's Disease, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Aurora ParodiDermatological Clinic, National Reference Center for Hansen's Disease, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Chiara PiubelliDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, 37024 Verona, Italy.ORCID 0000-0002-5739-3795
Francesca PerandinDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, 37024 Verona, Italy.
Ospedale Sacro Cuore Don Calabria · ITOspedale Policlinico San Martino · ITColorado State University · US

Funding

Fulbright Scholar Fulbright Scholar to Brazil 2019-2020Ministero della Salute Fondi Ricerca Corrente, project L3P2
6 · The paper itself

Abstract

backgroundLeprosy is a neglected tropical disease caused by

methodsWe calculate the cut-off using optimized O.D. thresholds, generated by receiver operating characteristics (ROC) curve analysis, testing 39 well-characterized sera obtained from lepromatous leprosy patients with strongly positive ND-O-BSAELISA titer and 39 sera from healthy non-endemic patients never exposed to

resultsWe detected 56.4% of SLALT and 22.5% of tuberculosis as positive, consistent with the literature.

conclusionThe ELISA based on ND-O-BSA may thus be considered a good option to be used in a non-endemic area as a screening tool in at risk population usually coming to our center.

Indexed as

ELISAEuropeleprosyND-O-BSA

Identifiers

PMID36015014
PMCPMC9415083
OpenAlexW4293678683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.