Evidence map›Paper›PMID 36014820›Full record

ArticleNutrients2022

Luteolin-7-

Dajung Ryu, Hye-Jin Jee, Sang-Yoon Kim, Seung-Hwan Hwang, Gam-Bang Pil, Yi-Sook Jung

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. International journal of molecular sciences · 2025
    Article
  5. Comprehensive Review ofFoods (Basel, Switzerland) · 2025
    Review
  6. Research advances inAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2025
    Review
  7. Review
  8. Article
  9. Luteolin-7-Molecules (Basel, Switzerland) · 2024
    Article
  10. Review
  11. Chinese herbal medicines · 2023
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. FermentedInternational journal of molecular sciences · 2022
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dajung RyuCollege of Pharmacy, Ajou University, Suwon 16499, Korea.
Hye-Jin JeeCollege of Pharmacy, Ajou University, Suwon 16499, Korea.
Sang-Yoon KimR&D Center, Huons Co., Ltd., 55 Hanyangdaehak-ro, Ansan 15588, Korea.ORCID 0000-0002-6918-0607
Seung-Hwan HwangR&D Center, Huons Co., Ltd., 55 Hanyangdaehak-ro, Ansan 15588, Korea.
Gam-Bang PilR&D Center, Huons Co., Ltd., 55 Hanyangdaehak-ro, Ansan 15588, Korea.
Yi-Sook JungCollege of Pharmacy, Ajou University, Suwon 16499, Korea.ORCID 0000-0001-7078-2077
Ajou University · KRHuons (South Korea) · KR

Funding

Ministry of Science and ICT (MSIT) 2020-JDH-2-CG-1
6 · The paper itself

Abstract

Stress exposure is a major risk factor for mental disorders such as depression. Because of the limitations of classical antidepressants such as side effects, low efficacy, and difficulty in long-term use, new natural medicines and bioactive molecules from plants with greater safety and efficacy have recently attracted attention. Luteolin-7-

Indexed as

Brain-Derived Neurotrophic FactorDepressionAdaptation, PsychologicalAnimalsAntidepressive AgentsDisease Models, AnimalHippocampusHumansLuteolinMiceSleep DeprivationStress, PsychologicalAntidepressive AgentsBrain-Derived Neurotrophic FactorLuteolinluteolin-7-O-glucuronideBDNF/TrkB/ERK/CREB signaling pathwaydepressionluteolin-7-O-glucuronidesleep deprivationstress

Identifiers

PMID36014820
PMCPMC9412559
OpenAlexW4291512670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.