ArticleNutrients2022
Higher Ultra-Processed Food Consumption Is Associated with Greater High-Sensitivity C-Reactive Protein Concentration in Adults: Cross-Sectional Results from the Melbourne Collaborative Cohort Study.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Association between ultra-processed foods and risk of cancer: a systematic review and meta-analysis.Frontiers in nutrition · 2023Pooled it
- Consumption of ultra-processed foods among patients with rheumatic diseases: a cross-sectional study and validation of the short screening questionnaire of highly processed food consumption (sQ-HPF) in the Greek language.Rheumatology international · 2026Article
- Pollutant Burden in Autism Spectrum Disorder: Mechanistic Convergence, Genetic Susceptibility, and Clinical Translation.Current issues in molecular biology · 2026Review
- Ultra-Processed Food Consumption Is Independently Associated with Higher HbA1c and Poor Glycemic Control in Adults with Type 2 Diabetes.Nutrients · 2026Observational
- Ultra-processed foods and cardiometabolic risk: from evidence to policy.npj metabolic health and disease · 2026Article
- Ultra-Processed Foods and the Cardiovascular-Kidney-Metabolic Continuum: Integrating Epidemiological, Multi-Omics, and Translational Evidence.Nutrients · 2026Review
- The Impact of Nutritional Status on Survival and Development of Sarcoidosis: A Scoping Review of Current Evidence and Research Gaps.Nutrients · 2026Review
- Association between ultra-processed food consumption and odds of depression, stress, and anxiety in adolescent girls: a cross-sectional study.BMC public health · 2026Article
- Does the definition of human ultra-processed foods apply to dog and cat foods? A review of pet food processing techniques, their impact on health, and a call for pet food processing classification.Frontiers in veterinary science · 2026Article
- Dampened inflammation and reduced risk of osteoarthritis among non-industrialized societies.Osteoarthritis and cartilage · 2026Review
- Ultra-Processed Food Consumption and Systemic Inflammatory Biomarkers: A Scoping Review.Nutrients · 2025Article
- Assessing Highly Processed Food Consumption in Patients with Inflammatory Bowel Disease: Application of the German Screening Questionnaire (sQ-HPF).Journal of clinical medicine · 2025Article
- Ultra-processed food consumption and cardiometabolic risk in Canada: a cross-sectional analysis of the Canadian health measures survey.Nutrition & metabolism · 2025Article
- Associations between ultra-processed food and drink consumption and biomarkers of chronic low-grade inflammation: exploring the mediating role of adiposity.European journal of nutrition · 2025Article
- Association between ultra-processed food consumption and inflammation: insights from the STANISLAS cohort.European journal of nutrition · 2025Article
- Association of ultra-processed food-related metabolites with selected biochemical markers in the UK Biobank.Nutrition journal · 2025Article
- Ultra-processed food consumption affects structural integrity of feeding-related brain regions independent of and via adiposity.npj metabolic health and disease · 2025Article
- Associations between ultra-processed food consumption and duration of exercise with psychological symptoms in Chinese adolescents: a nationwide cross-sectional survey.Frontiers in nutrition · 2025Article
- Review
- Ultra-Processed Food Consumption and Cardiometabolic Risk Factors in Children Living in Northeastern Brazil.Nutrients · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Few studies have examined associations between ultra-processed food intake and biomarkers of inflammation, and inconsistent results have been reported in the small number of studies that do exist. As such, further investigation is required. Methods: Cross-sectional baseline data from the Melbourne Collaborative Cohort Study (MCCS) were analysed (n = 2018). We applied the NOVA food classification system to data from a food frequency questionnaire (FFQ) to determine ultra-processed food intake (g/day). The outcome was high-sensitivity C-reactive protein concentration (hsCRP; mg/L). We fitted unadjusted and adjusted linear regression analyses, with sociodemographic characteristics and lifestyle- and health-related behaviours as covariates. Supplementary analyses further adjusted for body mass index (kg/m2). Sex was assessed as a possible effect modifier. Ultra-processed food intake was modelled as 100 g increments and the magnitude of associations expressed as estimated relative change in hsCRP concentration with accompanying 95% confidence intervals (95%CIs). Results: After adjustment, every 100 g increase in ultra-processed food intake was associated with a 4.0% increase in hsCRP concentration (95%CIs: 2.1−5.9%, p < 0.001). Supplementary analyses showed that part of this association was independent of body mass index (estimated relative change in hsCRP: 2.5%; 95%CIs: 0.8−4.3%, p = 0.004). No interaction was observed between sex and ultra-processed food intake. Conclusion: Higher ultra-processed food intake was cross-sectionally associated with elevated hsCRP, which appeared to occur independent of body mass index. Future prospective and intervention studies are necessary to confirm directionality and whether the observed association is causal.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.