Evidence map›Paper›PMID 36014590›Full record

ArticleMolecules (Basel, Switzerland)2022

Nanostructured Electrospun Polycaprolactone-Propolis Mats Composed of Different Morphologies for Potential Use in Wound Healing.

Agnes Chacor de Figueiredo, Javier Mauricio Anaya-Mancipe, Aline Oliveira da Silva de Barros, Ralph Santos-Oliveira, Marcos Lopes Dias, Rossana Mara da Silva Moreira Thiré

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Applications of propolis-based materials in wound healing.Archives of dermatological research · 2023
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Agnes Chacor de FigueiredoCOPPE/Program of Metallurgical and Materials Engineering-PEMM, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-599, RJ, Brazil.ORCID 0000-0003-0813-5674
Javier Mauricio Anaya-MancipeCOPPE/Program of Metallurgical and Materials Engineering-PEMM, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-599, RJ, Brazil.
Aline Oliveira da Silva de BarrosBrazilian Nuclear Energy Commission, Nuclear Engineering Institute-IEN, Rio de Janeiro 21941-906, RJ, Brazil.
Ralph Santos-OliveiraBrazilian Nuclear Energy Commission, Nuclear Engineering Institute-IEN, Rio de Janeiro 21941-906, RJ, Brazil.ORCID 0000-0002-0905-481X
Marcos Lopes DiasInstitute of Macromolecules Professora Eloisa Mano-IMA, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-598, RJ, Brazil.ORCID 0000-0003-1891-7530
Rossana Mara da Silva Moreira ThiréCOPPE/Program of Metallurgical and Materials Engineering-PEMM, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-599, RJ, Brazil.ORCID 0000-0003-0026-5431
Universidade Federal do Rio de Janeiro · BRUniversidade Estadual da Zona Oeste · BR

Funding

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro Rede NanoSaúde - E-26/210.139/2019Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro Temáticos - E-26/211.269/2021National Council for Scientific and Technological Development 308789/2020-2
6 · The paper itself

Abstract

This study aimed to investigate different types of morphologies obtained using the electrospinning process to produce a material that enables wound healing while performing a controlled release. Using benign solvents, the authors prepared and characterised electrospun polycaprolactone mats loaded with propolis, a popular extract in traditional medicine with potential for skin repair. Different morphologies were obtained from distinct storage periods of the solution before electrospinning to investigate the effect of PCL hydrolysis (average diameters of fibres and beads: 159.2-280.5 nm and 1.9-5.6 μm, respectively). Phytochemical and FTIR analyses of the extract confirmed propolis composition. GPC and viscosity analyses showed a decrease in polymer molecular weight over the storage period (about a 70% reduction over 14 days) and confirmed that it was responsible for the nanostructure diversity. Moreover, propolis acted as a lubricant agent, affecting the spun solutions' viscosity and the thermal properties and hydrophilicity of the mats. All samples were within the value range of the water vapour transpiration rate of the commercial products (1263.08 to 2179.84 g/m

Indexed as

NanofibersNanostructuresPropolisPlant ExtractsPolyestersWound HealingPlant ExtractspolycaprolactonePolyestersPropolisdrug deliveryelectrospinningmorphology structurespolycaprolactonepropolis

Identifiers

PMID36014590
PMCPMC9413572
OpenAlexW4292974302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.