Evidence map›Paper›PMID 36014478›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis, Anticancer Activities and Molecular Docking Studies of a Novel Class of 2-Phenyl-5,6,7,8-tetrahydroimidazo [1,2-

Otmane Bourzikat, Abdelmoula El Abbouchi, Hamza Ghammaz, Nabil El Brahmi, Elmostfa El Fahime, Arnaud Paris, Richard Daniellou, Franck Suzenet, Gérald Guillaumet, Saïd El Kazzouli

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Synthesis,Current medicinal chemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Otmane BourzikatEuromed Research Center, Euromed Faculty of Pharmacy, Euromed University of Fes (UEMF), Meknes Road, Fez 30000, Morocco.
Abdelmoula El AbbouchiEuromed Research Center, Euromed Faculty of Pharmacy, Euromed University of Fes (UEMF), Meknes Road, Fez 30000, Morocco.ORCID 0000-0002-0296-4044
Hamza GhammazCentre National de la Recherche Scientifique et Technique (CNRST), Angle Avenues des FAR et Allal El Fassi, Hay Ryad, Rabat 10102, Morocco.
Nabil El BrahmiEuromed Research Center, Euromed Faculty of Pharmacy, Euromed University of Fes (UEMF), Meknes Road, Fez 30000, Morocco.
Elmostfa El FahimeEuromed Research Center, Euromed Faculty of Pharmacy, Euromed University of Fes (UEMF), Meknes Road, Fez 30000, Morocco.
Arnaud ParisInstitut de Chimie Organique et Analytique, Université d'Orléans, UMR CNRS 7311, BP 6759, CEDEX 2, 45067 Orléans, France.
Richard DaniellouInstitut de Chimie Organique et Analytique, Université d'Orléans, UMR CNRS 7311, BP 6759, CEDEX 2, 45067 Orléans, France.ORCID 0000-0001-7296-3736
Franck SuzenetInstitut de Chimie Organique et Analytique, Université d'Orléans, UMR CNRS 7311, BP 6759, CEDEX 2, 45067 Orléans, France.ORCID 0000-0003-1394-1603
Gérald GuillaumetEuromed Research Center, Euromed Faculty of Pharmacy, Euromed University of Fes (UEMF), Meknes Road, Fez 30000, Morocco.
Saïd El KazzouliEuromed Research Center, Euromed Faculty of Pharmacy, Euromed University of Fes (UEMF), Meknes Road, Fez 30000, Morocco.ORCID 0000-0001-5021-3571
Université d'Orléans · FREuro-Mediterranean University of Fes · MACentre National pour la Recherche Scientifique et Technique (CNRST) · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, new 2-phenyl-5,6,7,8-tetrahydroimidazo [1,2-

Indexed as

Antineoplastic AgentsNeoplasmsPyridazinesCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorEtoposideFluorouracilHumansMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipSulfanilamideSulfonamidesAntineoplastic AgentsEtoposideFluorouracilPyridazinesSulfanilamideSulfonamides2-phenyl-5,6,7,8-tetrahydroimidazo [1,2-b]pyridazineanticancer activityhuman cancer cell linessulfonamides

Identifiers

PMID36014478
PMCPMC9416205
OpenAlexW4292261735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.