ReviewMolecules (Basel, Switzerland)2022
Maize Flavonoid Biosynthesis, Regulation, and Human Health Relevance: A Review.
Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Pooled it
- Decoding the Temporal Accumulation Pattern of Anthocyanins From Dynamic Expression of Purple aleurone1 Gene in Blue- and Red-kernel Maize Breeding Lines.Applied biochemistry and biotechnology · 2026Article
- North American and Andean Indigenous Plant-Based Foods and Their Contemporary Scientific Rationale for Health Improvement.Current developments in nutrition · 2026Article
- Article
- Metabolomic Profiling of Native Yucatan Maizes (Journal of agricultural and food chemistry · 2026Article
- Integrated transcriptomic and metabolomic profiles analysis reveals a potential gene-metabolite network associated with anthocyanin-mediated color variation in maize kernels.Frontiers in plant science · 2026Article
- Unraveling the genetic and molecular mechanisms of anthocyanin biosynthesis and accumulation in maize kernels.Frontiers in plant science · 2026Review
- Anthocyanin Synthesis Capability of Maize Cultivars Is Associated with Their Photosynthetic Carbon Partitioning for Growth Adaptability Under Low Phosphorus.Plants (Basel, Switzerland) · 2025Article
- Variability in Anthocyanin Expression in Native Maize: PurplePlants (Basel, Switzerland) · 2025Article
- Temporal expression of3 Biotech · 2025Article
- Comparative transcriptomic analysis of heterotic maize development during kernel filling.Plant molecular biology · 2025Article
- Article
- Regulation of Flavonoid Biosynthesis by the MYB-bHLH-WDR (MBW) Complex in Plants and Its Specific Features in Cereals.International journal of molecular sciences · 2025Review
- Integrated Transcriptome and Metabolome Analysis Reveals Mechanism of Flavonoid Synthesis During Low-Temperature Storage of Sweet Corn Kernels.Foods (Basel, Switzerland) · 2024Article
- An ARF gene mutation creates flint kernel architecture in dent maize.Nature communications · 2024Article
- Bioactive Compounds from Pigmented Corn (Biomolecules · 2024Review
- Backcrossing Modulates the Metabolic Profiles of Anthocyanin-Pigmented 'Vitamaize' Lines Derived from Elite Maize Lines.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024Article
- Cloned genes and genetic regulation of anthocyanin biosynthesis in maize, a comparative review.Frontiers in plant science · 2024Review
- Maize hydroxycinnamic acids: unveiling their role in stress resilience and human health.Frontiers in nutrition · 2024Review
- A Review of Classification, Biosynthesis, Biological Activities and Potential Applications of Flavonoids.Molecules (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maize is one of the most important crops for human and animal consumption and contains a chemical arsenal essential for survival: flavonoids. Moreover, flavonoids are well known for their beneficial effects on human health. In this review, we decided to organize the information about maize flavonoids into three sections. In the first section, we include updated information about the enzymatic pathway of maize flavonoids. We describe a total of twenty-one genes for the flavonoid pathway of maize. The first three genes participate in the general phenylpropanoid pathway. Four genes are common biosynthetic early genes for flavonoids, and fourteen are specific genes for the flavonoid subgroups, the anthocyanins, and flavone C-glycosides. The second section explains the tissue accumulation and regulation of flavonoids by environmental factors affecting the expression of the MYB-bHLH-WD40 (MBW) transcriptional complex. The study of transcription factors of the MBW complex is fundamental for understanding how the flavonoid profiles generate a palette of colors in the plant tissues. Finally, we also include an update of the biological activities of C3G, the major maize anthocyanin, including anticancer, antidiabetic, and antioxidant effects, among others. This review intends to disclose and integrate the existing knowledge regarding maize flavonoid pigmentation and its relevance in the human health sector.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.