Evidence map›Paper›PMID 36014405›Full record

ArticleMolecules (Basel, Switzerland)2022

Novel Organic Salts Based on Mefloquine: Synthesis, Solubility, Permeability, and In Vitro Activity against

Dário Silva, Márcio V C Lopes, Željko Petrovski, Miguel M Santos, Jussevania P Santos, Sueli F Yamada-Ogatta, Marcelle L F Bispo, Marcus V N de Souza, Ana Rita C Duarte, Maria C S Lourenço and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Dário SilvaLAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, 2829-516 Caparica, Portugal.ORCID 0000-0002-2565-089X
Márcio V C LopesInstituto de Química, Universidade Federal do Rio de Janeiro, Av. Athos da Silveira Ramos 149, Cidade Universitaria, Rio de Janeiro 21941-909, Brazil.
Željko PetrovskiLAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, 2829-516 Caparica, Portugal.ORCID 0000-0002-8104-7008
Miguel M SantosLAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, 2829-516 Caparica, Portugal.ORCID 0000-0001-8973-1595
Jussevania P SantosDepartamento de Microbiologia, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid (PR 445), Km 380, Campus Universitário, Londrina 86057-970, Brazil.
Sueli F Yamada-OgattaDepartamento de Microbiologia, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid (PR 445), Km 380, Campus Universitário, Londrina 86057-970, Brazil.
Marcelle L F BispoDepartamento de Microbiologia, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid (PR 445), Km 380, Campus Universitário, Londrina 86057-970, Brazil.
Marcus V N de SouzaFioCruz-Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos-Far-Manguinhos, Rua Sizenando Nabuco, 100, Manguinhos, Rio de Janeiro 21041-250, Brazil.ORCID 0000-0003-1566-8110
Ana Rita C DuarteLAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, 2829-516 Caparica, Portugal.
Maria C S LourençoInstituto de Pesquisas Clínica Evandro Chagas-IPEC, Av. Brasil, 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
Raoni Schroeder B GonçalvesInstituto de Química, Universidade Federal do Rio de Janeiro, Av. Athos da Silveira Ramos 149, Cidade Universitaria, Rio de Janeiro 21941-909, Brazil.
Luis C BrancoLAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, 2829-516 Caparica, Portugal.ORCID 0000-0003-2520-1151
Rede de Química e Tecnologia · PTUniversidade Estadual de Londrina · BRUniversidade Federal do Rio de Janeiro · BRFundação Oswaldo Cruz · BRInstituto Evandro Chagas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of novel pharmaceutical tools to efficiently tackle tuberculosis is the order of the day due to the rapid development of resistant strains of

Indexed as

AntimalarialsMycobacterium tuberculosisHEPESMefloquinePermeabilitySaltsSolubilityAntimalarialsHEPESMefloquineSaltsAPI-OSILsionic liquidsmefloquinepolymorphismtuberculosis

Identifiers

PMID36014405
PMCPMC9412322
OpenAlexW4291512189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.