Evidence map›Paper›PMID 36014368›Full record

ArticleMolecules (Basel, Switzerland)2022

Investigation of the

Juliette Balieu, Jae-Wan Jung, Philippe Chan, George P Lomonossoff, Patrice Lerouge, Muriel Bardor

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  3. Article
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  5. Article
  6. Tailored Viral-like Particles as Drivers of Medical Breakthroughs.International journal of molecular sciences · 2024
    Review
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  8. Review
  9. Article
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Juliette BalieuUniversité de Rouen Normandie, Laboratoire GlycoMEV UR 4358, SFR Normandie Végétal FED 4277, Innovation Chimie Carnot, 76000 Rouen, France.
Jae-Wan JungDepartment of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Philippe ChanUniversité de Rouen Normandie, INSERM US 51, CNRS UAR 2026, HeRacLeS, 76000 Rouen, France.
George P LomonossoffDepartment of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.ORCID 0000-0003-0700-906X
Patrice LerougeUniversité de Rouen Normandie, Laboratoire GlycoMEV UR 4358, SFR Normandie Végétal FED 4277, Innovation Chimie Carnot, 76000 Rouen, France.
Muriel BardorUniversité de Rouen Normandie, Laboratoire GlycoMEV UR 4358, SFR Normandie Végétal FED 4277, Innovation Chimie Carnot, 76000 Rouen, France.ORCID 0000-0002-0966-903X
Centre National de la Recherche Scientifique · FRJohn Innes Centre · GBLaboratoire de Glycobiologie et Matrice Extracellulaire Végétale

Funding

European Union's Horizon 2020 Research and Innovation Programme 774078 Pharma Factory project
6 · The paper itself

Abstract

The emergence of the SARS-CoV-2 coronavirus pandemic in China in late 2019 led to the fast development of efficient therapeutics. Of the major structural proteins encoded by the SARS-CoV-2 genome, the SPIKE (S) protein has attracted considerable research interest because of the central role it plays in virus entry into host cells. Therefore, to date, most immunization strategies aim at inducing neutralizing antibodies against the surface viral S protein. The SARS-CoV-2 S protein is heavily glycosylated with 22 predicted

Indexed as

COVID-19SARS-CoV-2AnimalsGlycosylationHumansMammalsNicotianaPolysaccharidesSpike Glycoprotein, CoronavirusVirionPolysaccharidesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2biologicsbiopharmaceuticalsCOVIDmass spectrometryN-glycansNicotiana benthamianaplant molecular farmingSPIKEvaccine

Identifiers

PMID36014368
PMCPMC9412417
OpenAlexW4290999195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.