Evidence map›Paper›PMID 36014334›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis and Biological Activity of Unsymmetrical Monoterpenylhetaryl Disulfides.

Denis V Sudarikov, Yulia V Gyrdymova, Alexander V Borisov, Julia M Lukiyanova, Roman V Rumyantcev, Oksana G Shevchenko, Diana R Baidamshina, Nargiza D Zakarova, Airat R Kayumov, Ekaterina O Sinegubova and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Increasing the Efficacy of Treatment ofAntibiotics (Basel, Switzerland) · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Denis V SudarikovInstitute of Chemistry, FRC "Komi Scientific Centre", Ural Branch of the Russian Academy of Sciences, Pervomayskaya St. 48, 167000 Syktyvkar, Komi Republic, Russia.ORCID 0000-0001-5640-6956
Yulia V GyrdymovaInstitute of Chemistry, FRC "Komi Scientific Centre", Ural Branch of the Russian Academy of Sciences, Pervomayskaya St. 48, 167000 Syktyvkar, Komi Republic, Russia.
Alexander V BorisovDepartment of Chemistry, Nizhny Novgorod State Technical University n.a. R.E. Alekseev, 24 Minin St., 603155 Nizhny Novgorod, Russia.ORCID 0000-0003-1765-5241
Julia M LukiyanovaDepartment of Chemistry, Nizhny Novgorod State Technical University n.a. R.E. Alekseev, 24 Minin St., 603155 Nizhny Novgorod, Russia.
Roman V RumyantcevRazuvaev Institute of Organometallic Chemistry, Russian Academy of Sciences, Tropinina 49, 603950 Nizhny Novgorod, Russia.ORCID 0000-0003-0198-3806
Oksana G ShevchenkoCenter of Collective Usage "Molecular Biology", Institute of Biology, Komi Science Centre, Ural Branch of Russian Academy of Sciences, 28 Kommunisticheskaya Street, 167982 Syktyvkar, Russia.ORCID 0000-0001-5331-3201
Diana R BaidamshinaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 18 Kremlevskaya St., 420008 Kazan, Russia.
Nargiza D ZakarovaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 18 Kremlevskaya St., 420008 Kazan, Russia.
Airat R KayumovInstitute of Fundamental Medicine and Biology, Kazan Federal University, 18 Kremlevskaya St., 420008 Kazan, Russia.ORCID 0000-0001-7195-1557
Ekaterina O SinegubovaSaint Petersburg Pasteur Research Institute of Epidemiology and Microbiology, 14 Mira St., 197101 Saint Petersburg, Russia.ORCID 0000-0001-9490-2280
Alexandrina S VolobuevaSaint Petersburg Pasteur Research Institute of Epidemiology and Microbiology, 14 Mira St., 197101 Saint Petersburg, Russia.
Vladimir V ZarubaevSaint Petersburg Pasteur Research Institute of Epidemiology and Microbiology, 14 Mira St., 197101 Saint Petersburg, Russia.ORCID 0000-0002-5224-3771
Svetlana A RubtsovaInstitute of Chemistry, FRC "Komi Scientific Centre", Ural Branch of the Russian Academy of Sciences, Pervomayskaya St. 48, 167000 Syktyvkar, Komi Republic, Russia.

Funding

Russian Science Foundation 21-13-00245
6 · The paper itself

Abstract

New unsymmetrical monoterpenylhetaryl disulfides based on heterocyclic disulfides and monoterpene thiols were synthesized for the first time in 48-88% yields. Hydrolysis of disulfides with fragments of methyl esters of 2-mercaptonicotinic acid was carried out in 73-95% yields. The obtained compounds were evaluated for antioxidant, antibacterial, antifungal activity, cytotoxicity and mutagenicity.

Indexed as

DisulfidesSulfhydryl CompoundsAntifungal AgentsAntioxidantsEstersMutagensAntifungal AgentsAntioxidantsDisulfidesEstersMutagensSulfhydryl Compoundsantibacterialantifungal activityantioxidantcytotoxicitymonoterpenylhetaryl disulfidesmutagenicityunsymmetrical

Identifiers

PMID36014334
PMCPMC9416111

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.