Evidence map›Paper›PMID 36014325›Full record

ReviewMolecules (Basel, Switzerland)2022

Photoactive Herbal Compounds: A Green Approach to Photodynamic Therapy.

Cheruthazhakkat Sulaiman, Blassan P George, Indira Balachandran, Heidi Abrahamse

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Cancer and Traditional Medicine: An Integrative Approach.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  12. Review
  13. Review
  14. Divulging the potency of naturally derived photosensitizers in green PDT: an inclusive review Of mechanisms, advantages, and future prospects.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  15. Article
  16. Review
  17. Article
  18. Foods (Basel, Switzerland) · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Cheruthazhakkat SulaimanPhytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal 676503, India.ORCID 0000-0002-3643-6290
Blassan P GeorgeLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein 2028, South Africa.
Indira BalachandranPhytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal 676503, India.
Heidi AbrahamseLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein 2028, South Africa.ORCID 0000-0001-5002-827X
Arya Vaidya Sala · INUniversity of Johannesburg · ZA

Funding

the South African Medical Research Council through its Division of Re-search Capacity Development under the Research Capacity Development Initiative from funding received from the South African National Treasury. SAMRC EIP007/2021the South African Research Chairs Initiative of the Department of Science and Technology and the National Research Foundation of South Africa 98337
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is a minimally invasive, alternative, and promising treatment for various diseases, including cancer, actinic keratosis, Bowen's disease, macular degeneration, and atherosclerotic plaques. PDT involves three different components, photosensitizers (PS), molecular oxygen, and light. The photoactivation of administered PSs using a specific wavelength of light in the presence of molecular oxygen leads to the generation of reactive oxygen species that leads to tumour cell death. Photosensitizing potentials of many commercially available compounds have been reported earlier. However, the possibilities of PDT using herbal medicines, which contain many photosensitizing phytochemicals, are not much explored. Medicinal plants with complex phytochemical compound mixtures have the benefit over single compounds or molecules in the treatment of many diseases with the benefit of low or reduced toxic side effects. This review emphasizes the role of various herbal medicines either alone or in combination to enhance the therapeutic outcome of photodynamic therapy.

Indexed as

Keratosis, ActinicPhotochemotherapySkin NeoplasmsHumansOxygenPhotosensitizing AgentsPhytochemicalsOxygenPhotosensitizing AgentsPhytochemicalsherbal medicinenatural productsphotodynamic therapyphotosensitizersphytochemicalsplants

Identifiers

PMID36014325
PMCPMC9413332
OpenAlexW4293512356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.