Evidence map›Paper›PMID 36014146›Full record

ArticleMicromachines2022

A Portable 'Plug-and-Play' Fibre Optic Sensor for In-Situ Measurements of pH Values for Microfluidic Applications.

Rahul Kumar, Hien Nguyen, Bruno Rente, Christabel Tan, Tong Sun, Kenneth T V Grattan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rahul KumarDepartment of Electrical and Electronic Engineering, University of London, London EC1V 0HB, UK.
Hien NguyenDepartment of Electrical and Electronic Engineering, University of London, London EC1V 0HB, UK.
Bruno RenteDepartment of Electrical and Electronic Engineering, University of London, London EC1V 0HB, UK.
Christabel TanSchool of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UK.
Tong SunDepartment of Electrical and Electronic Engineering, University of London, London EC1V 0HB, UK.
Kenneth T V GrattanDepartment of Electrical and Electronic Engineering, University of London, London EC1V 0HB, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microfluidics is used in many applications ranging from chemistry, medicine, biology and biomedical research, and the ability to measure pH values in-situ is an important parameter for creating and monitoring environments within a microfluidic chip for many such applications. We present a portable, optical fibre-based sensor for monitoring the pH based on the fluorescent intensity change of an acrylamidofluorescein dye, immobilized on the tip of a multimode optical fibre, and its performance is evaluated in-situ in a microfluidic channel. The sensor showed a sigmoid response over the pH range of 6.0-8.5, with a maximum sensitivity of 0.2/pH in the mid-range at pH 7.5. Following its evaluation, the sensor developed was used in a single microfluidic PDMS channel and its response was monitored for various flow rates within the channel. The results thus obtained showed that the sensor is sufficiently robust and well-suited to be used for measuring the pH value of the flowing liquid in the microchannel, allowing it to be used for a number of practical applications in 'lab-on-a-chip' applications where microfluidics are used. A key feature of the sensor is its simplicity and the ease of integrating the sensor with the microfluidic channel being probed.

Indexed as

fluorescent sensormicrofluidicsoptical fibre sensorpH sensor

Identifiers

PMID36014146
PMCPMC9416338

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.