Evidence map›Paper›PMID 36014098›Full record

ArticleMicroorganisms2022

Phylogenomic Placement of American Southwest-Associated Clinical and Veterinary Isolates Expands Evidence for Distinct

Juan Monroy-Nieto, Jolene R Bowers, Parker Montfort, Guillermo Adame, Constanza Giselle Taverna, Hayley Yaglom, Jane E Sykes, Shane Brady, A Brian Mochon, Wieland Meyer and 2 more

Abstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. An Emerging Infectious Yeast to Watch:Journal of fungi (Basel, Switzerland) · 2025
    Review
  2. DETECTION OF SARS-COV-2 IN A SQUIRREL MONKEY (Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians · 2024
    Article
  3. Genotyping Analysis ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Pulmonary Cryptococcosis.Journal of fungi (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Juan Monroy-NietoPathogen and Microbiome Division, Translational Genomics Research Institute, Flagstaff, AZ 86005, USA.ORCID 0000-0002-8692-1286
Jolene R BowersPathogen and Microbiome Division, Translational Genomics Research Institute, Flagstaff, AZ 86005, USA.
Parker MontfortPathogen and Microbiome Division, Translational Genomics Research Institute, Flagstaff, AZ 86005, USA.
Guillermo AdameArizona Department of Health Services, Phoenix, AZ 85007, USA.ORCID 0000-0003-0582-7827
Constanza Giselle TavernaInstituto Nacional de Enfermedades Infecciosas "Dr. Carlos G. Malbrán", Buenos Aires C1282AFF, Argentina.
Hayley YaglomPathogen and Microbiome Division, Translational Genomics Research Institute, Flagstaff, AZ 86005, USA.
Jane E SykesDepartment of Medicine & Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616, USA.
Shane BradyArizona Department of Health Services, Phoenix, AZ 85007, USA.
A Brian MochonDepartment of Pathology, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ 85721, USA.
Wieland MeyerSydney Medical School, University of Sydney, Sydney, NSW 2050, Australia.
Kenneth KomatsuArizona Department of Health Services, Phoenix, AZ 85007, USA.
David M EngelthalerPathogen and Microbiome Division, Translational Genomics Research Institute, Flagstaff, AZ 86005, USA.

Funding

The NARBHA Institute NA
6 · The paper itself

Abstract

Whole-genome sequencing has advanced our understanding of the population structure of the pathogenic species complex Cryptococcus gattii, which has allowed for the phylogenomic specification of previously described major molecular type groupings and novel lineages. Recently, isolates collected in Mexico in the 1960s were determined to be genetically distant from other known molecular types and were classified as VGVI. We sequenced four clinical isolates and one veterinary isolate collected in the southwestern United States and Argentina from 2012 to 2021. Phylogenomic analysis groups these genomes with those of the Mexican VGVI isolates, expanding VGVI into a clade and establishing this molecular type as a clinically important population. These findings also potentially expand the known Cryptococcus ecological range with a previously unrecognized endemic area.

Indexed as

Cryptococcusmolecular typephylogenomicsVGVIwhole-genome sequencing

Identifiers

PMID36014098
PMCPMC9412296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.