Evidence map›Paper›PMID 36014058›Full record

ArticleMicroorganisms2022

Combined Orthoplastic Approach in Fracture-Related Infections of the Distal Tibia.

Andrea Sambri, Marco Pignatti, Sara Tedeschi, Maria Elisa Lozano Miralles, Claudio Giannini, Michele Fiore, Matteo Filippini, Riccardo Cipriani, Pierluigi Viale, Massimiliano De Paolis

Abstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Surgical management of chronic osteomyelitis: Organisms, recurrence and treatment outcome.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrea SambriOrthopaedics Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.ORCID 0000-0002-2099-8547
Marco PignattiPlastic Surgery Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.
Sara TedeschiDepartment of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.
Maria Elisa Lozano MirallesPlastic Surgery Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.
Claudio GianniniOrthopaedics Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.
Michele FioreOrthopaedics Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.ORCID 0000-0003-0546-670X
Matteo FilippiniOrthopaedics Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.
Riccardo CiprianiPlastic Surgery Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.
Pierluigi VialeDepartment of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.
Massimiliano De PaolisOrthopaedics Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.ORCID 0000-0002-6182-9870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This series reports on the treatment of distal tibia (DT) fracture-related infections (FRI) with a combined orthoplastic approach. Thirteen patients were included. In eight patients with extensive bone involvement and in those with a non-healed fracture, the DT was resected ("staged approach"). In five cases, the DT was preserved ("single-stage approach"). A wide debridement was performed, and the cavity was filled with antibiotic-loaded PerOssal beads. All patients had a soft-tissue defect covered by a free vascularized flap (anterolateral thigh perforator flap in eight cases, latissimus dorsi flap in five). At the final follow-up (mean 25 months, range, 13-37), no infection recurrence was observed. In one patient, the persistence of infection was observed, and the patient underwent a repeated debridement. In two cases, a voluminous hematoma was observed. However, none of these complications impacted the final outcome. The successful treatment of FRI depends on proper debridement and obliteration of dead spaces with a flap. Therefore, when dealing with DT FRI, debridement of infected bone and soft tissues must be as radical as required, with no fear of the need for massive reconstructions.

Indexed as

allograftarthrodesischronic osteomyelitisdistal tibiafree flaporthoplasticperossal

Identifiers

PMID36014058
PMCPMC9414956

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.