Evidence map›Paper›PMID 36013992›Full record

ArticleMicroorganisms2022

Consortium of Indigenous Fecal Bacteria in the Treatment of Metabolic Syndrome.

Elena Ermolenko, Marina Kotyleva, Anna Kotrova, Sergey Tichonov, Nadezhda Lavrenova, Lyubov Voropaeva, Yulia Topalova, Alena Karaseva, Daniil Azarov, Konstantin Ermolenko and 4 more

Abstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elena ErmolenkoFederal State Budgetary Institution "Institute of Experimental Medicine", 197376 Saint-Petersburg, Russia.
Marina KotylevaFederal State Budgetary Institution "Institute of Experimental Medicine", 197376 Saint-Petersburg, Russia.
Anna KotrovaMedical Faculty, Saint-Petersburg State University, 199034 Saint-Petersburg, Russia.
Sergey TichonovDepartment of Internal Medicine, Clinical Pharmacology and Nephrology, North-Western State Medical University named after I.I. Mechnikov, 195067 Saint-Petersburg, Russia.
Nadezhda LavrenovaFederal State Budgetary Institution "Institute of Experimental Medicine", 197376 Saint-Petersburg, Russia.
Lyubov VoropaevaFederal State Budgetary Institution "Institute of Experimental Medicine", 197376 Saint-Petersburg, Russia.ORCID 0000-0002-0052-0896
Yulia TopalovaMedical Faculty, Saint-Petersburg State University, 199034 Saint-Petersburg, Russia.
Alena KarasevaFederal State Budgetary Institution "Institute of Experimental Medicine", 197376 Saint-Petersburg, Russia.
Daniil AzarovFederal State Budgetary Institution "Institute of Experimental Medicine", 197376 Saint-Petersburg, Russia.
Konstantin ErmolenkoPediatric Research and Clinical Center for Infectious Diseases, 197022 Saint-Petersburg, Russia.
Dmitrii DruzhininskiiAlmazov National Medical Research Centre, 197341 Saint-Petersburg, Russia.ORCID 0000-0002-9701-0306
Alexander DmitrievFederal State Budgetary Institution "Institute of Experimental Medicine", 197376 Saint-Petersburg, Russia.
Alexander ShishkinMedical Faculty, Saint-Petersburg State University, 199034 Saint-Petersburg, Russia.
Alexander SuvorovFederal State Budgetary Institution "Institute of Experimental Medicine", 197376 Saint-Petersburg, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The features of gut microbiota in metabolic syndrome (MS) and ways to correct it using autoprobiotics, based on indigenous bacteria obtained from fecal samples of the host, remain unexplored. The aim of the study was to investigate the effectiveness of an indigenous consortium (IC) of fecal bacteria in treatment of patients with MS. The study was carried out on 36 patients with MS, manifested with abdominal obesity, eating disorders, dyslipidemia, and hypertension. The control group was formed by 20 healthy volunteers. Samples of IC and gut microbiota content were examined by qPCR and metagenome (16S rRNA) analysis before and after therapy. The decrease in anthropometric parameters of obesity, liver enzyme level correction, reduction in C reactive protein and triglyceride concentrations were revealed after IC usage. The decrease in genera

Indexed as

autoprobioticsBacteroides fragilisBifidobacterium spp.dyslipidemiaeating disordersindigenous consortiumLactobacillus spp.obesity

Identifiers

PMID36013992
PMCPMC9414820

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.