Evidence map›Paper›PMID 36013552›Full record

ArticleMedicina (Kaunas, Lithuania)2022

Dual-Energy CT-Based Bone Mineral Density Has Practical Value for Osteoporosis Screening around the Knee.

Keun Young Choi, Sheen-Woo Lee, Yong In, Man Soo Kim, Yong Deok Kim, Seung-Yeol Lee, Jin-Woo Lee, In Jun Koh

Open access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 32 citations in OpenAlex.

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  9. Can Hounsfield Unit Evaluation of Preoperative CT Scans Predict Surgeon's Preference of Cementless Fixation in Total Knee Arthroplasty?Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Keun Young ChoiJoint Replacement Center, Eunpyeong St. Mary's Hospital, Seoul 03312, Korea.
Sheen-Woo LeeDepartment of Radiology, Eunpyeong St. Mary's Hospital, Seoul 03312, Korea.ORCID 0000-0002-7861-7153
Yong InDepartment of Orthopaedic Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-5932-3934
Man Soo KimDepartment of Orthopaedic Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-1374-9964
Yong Deok KimJoint Replacement Center, Eunpyeong St. Mary's Hospital, Seoul 03312, Korea.ORCID 0000-0003-3321-1085
Seung-Yeol LeeJoint Replacement Center, Eunpyeong St. Mary's Hospital, Seoul 03312, Korea.
Jin-Woo LeeJoint Replacement Center, Eunpyeong St. Mary's Hospital, Seoul 03312, Korea.
In Jun KohJoint Replacement Center, Eunpyeong St. Mary's Hospital, Seoul 03312, Korea.ORCID 0000-0002-7941-1587
Catholic University of Korea · KRSt. Mary's Hospital · USThe Catholic University of Korea Seoul St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Adequate bone quality is essential for long term biologic fixation of cementless total knee arthroplasty (TKA). Recently, vertebral bone quality evaluation using dual-energy computed tomography (DECT) has been introduced. However, the DECT bone mineral density (BMD) in peripheral skeleton has not been correlated with Hounsfield units (HU) or central dual-energy X-ray absorptiometry (DXA), and the accuracy remains unclear. Materials and methods: Medical records of 117 patients who underwent TKA were reviewed. DXA was completed within three months before surgery. DECT was performed with third-generation dual source CT in dual-energy mode. Correlations between DXA, DECT BMD and HU for central and periarticular regions were analyzed. Receiver operating characteristic (ROC) curves were plotted and area under the curve (AUC), optimal threshold, and sensitivity and specificity of each region of interest (ROI) were calculated. Results: Central DXA BMD was correlated with DECT BMD and HU in ROIs both centrally and around the knee (all p < 0.01). The diagnostic accuracy of DECT BMD was higher than that of DECT HU and was also higher when the T-score for second lumbar vertebra (L2), rather than for the femur neck, was used as the reference standard (all AUC values: L2 > femur neck; DECT BMD > DECT HU, respectively). Using the DXA T-score at L2 as the reference standard, the optimal DECT BMD cut-off values for osteoporosis were 89.2 mg/cm3 in the distal femur and 78.3 mg/cm3 in the proximal tibia. Conclusion: Opportunistic volumetric BMD assessment using DECT is accurate and relatively simple, and does not require extra equipment. DECT BMD and HU are useful for osteoporosis screening before cementless TKA.

Indexed as

Bone DensityOsteoporosisAbsorptiometry, PhotonFemur NeckHumansLumbar VertebraeRetrospective StudiesTomography, X-Ray Computedbone mineral densitydual-energy CTHounsfield unitopportunistic CTvolumetric phantomless BMD

Identifiers

PMID36013552
PMCPMC9416743
OpenAlexW4290999185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.