ArticleLife (Basel, Switzerland)2022
The Role of the Precuneus in Human Spatial Updating in a Real Environment Setting-A cTBS Study.
Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Effects of transcranial magnetic stimulation on spatial memory: a systematic review across animal and human studies.Frontiers in behavioral neuroscience · 2026Pooled it
- A systematic review and coordinate-based meta-analysis of resting-state fMRI in athletes from open and closed skills sports.Scientific reports · 2025Pooled it
- Neural networks underlying magnitude perception: a specific meta-analysis of fMRI studies.Cerebral cortex (New York, N.Y. : 1991) · 2025Pooled it
- Bilateral intermittent theta burst stimulation over the primary motor cortex improves motor and affective symptoms via thalamic network reintegration in mid-stage Parkinson's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Trial
- The Spatial Updating Mechanism of Different Field Cognitive Styles in Various Scene Layouts: Evidence from Behavior and fNIRS.Behavioral sciences (Basel, Switzerland) · 2026Article
- EEG activities and connectivities associated with surtitle presentation during live opera viewing: an exploratory analysis of cognitive absorption.Scientific reports · 2026Article
- Preference for directional responding in a virtual Morris water task is associated with increased precuneus activation in adolescent humans.Behavioural brain research · 2026Article
- Cortical dynamics are differentially associated with decision-making strategies in human wayfinding: An EEG study.Cognitive, affective & behavioral neuroscience · 2026Article
- Spatial contexts with reliable neural representations support reinstatement of subsequently placed objects.Nature human behaviour · 2026Article
- Differential Speed and Accuracy Trade-Off in Working Memory Retrieval and Bilateral Precuneus Between Older Men and Women.Brain and behavior · 2025Article
- How sturdy is your memory palace? Reliable room representations predict subsequent reinstatement of placed objects.bioRxiv : the preprint server for biology · 2025Article
- Brain plasticity associated with prolonged shooting training: a multimodal neuroimaging investigation from a cross-sectional study.Frontiers in human neuroscience · 2025Article
- Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Article
- How embodied is cognition? fMRI and behavioral evidence for common neural resources underlying motor planning and mental rotation of bodily stimuli.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As we move through an environment, we update positions of our body relative to other objects, even when some objects temporarily or permanently leave our field of view-this ability is termed egocentric spatial updating and plays an important role in everyday life. Still, our knowledge about its representation in the brain is still scarce, with previous studies using virtual movements in virtual environments or patients with brain lesions suggesting that the precuneus might play an important role. However, whether this assumption is also true when healthy humans move in real environments where full body-based cues are available in addition to the visual cues typically used in many VR studies is unclear. Therefore, in this study we investigated the role of the precuneus in egocentric spatial updating in a real environment setting in 20 healthy young participants who underwent two conditions in a cross-over design: (a) stimulation, achieved through applying continuous theta-burst stimulation (cTBS) to inhibit the precuneus and (b) sham condition (activated coil turned upside down). In both conditions, participants had to walk back with blindfolded eyes to objects they had previously memorized while walking with open eyes. Simplified trials (without spatial updating) were used as control condition, to make sure the participants were not affected by factors such as walking blindfolded, vestibular or working memory deficits. A significant interaction was found, with participants performing better in the sham condition compared to real stimulation, showing smaller errors both in distance and angle. The results of our study reveal evidence of an important role of the precuneus in a real-environment egocentric spatial updating; studies on larger samples are necessary to confirm and further investigate this finding.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.