Evidence map›Paper›PMID 36013364›Full record

ReviewLife (Basel, Switzerland)2022

Prevention and Management Strategies for Diabetic Neuropathy.

Sasha Smith, Pasha Normahani, Tristan Lane, David Hohenschurz-Schmidt, Nick Oliver, Alun Huw Davies

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Review
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  7. Review
  8. Article
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  11. Review
  12. An Overview on Diabetic Neuropathy.Current diabetes reviews · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sasha SmithSection of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London W6 8RF, UK.ORCID 0000-0001-9843-5368
Pasha NormahaniSection of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London W6 8RF, UK.
Tristan LaneSection of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London W6 8RF, UK.ORCID 0000-0002-8681-7075
David Hohenschurz-SchmidtPain Research Group, Department of Surgery and Cancer, Imperial College London, London SW10 9NH, UK.ORCID 0000-0002-1964-6069
Nick OliverSection of Metabolic Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London W2 1PG, UK.ORCID 0000-0003-3525-3633
Alun Huw DaviesSection of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London W6 8RF, UK.
Imperial College Healthcare NHS Trust · GBCambridge University Hospitals NHS Foundation Trust · GBImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic neuropathy (DN) is a common complication of diabetes that is becoming an increasing concern as the prevalence of diabetes rapidly rises. There are several types of DN, but the most prevalent and studied type is distal symmetrical polyneuropathy, which is the focus of this review and is simply referred to as DN. It can lead to a wide range of sensorimotor and psychosocial symptoms and is a major risk factor for diabetic foot ulceration and Charcot neuropathic osteoarthropathy, which are associated with high rates of lower limb amputation and mortality. The prevention and management of DN are thus critical, and clinical guidelines recommend several strategies for these based on the best available evidence. This article aims to provide a narrative review of DN prevention and management strategies by discussing these guidelines and the evidence that supports them. First, the epidemiology and diverse clinical manifestations of DN are summarized. Then, prevention strategies such as glycemic control, lifestyle modifications and footcare are discussed, as well as the importance of early diagnosis. Finally, neuropathic pain management strategies and promising novel therapies under investigation such as neuromodulation devices and nutraceuticals are reviewed.

Indexed as

diabetesdiabetic neuropathydiagnostic evaluationdistal symmetrical polyneuropathyfootcareglycemic controllifestyle modificationsneuromodulationnutraceuticalspain management

Identifiers

PMID36013364
PMCPMC9410148
OpenAlexW4289711908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.