Evidence map›Paper›PMID 36013355›Full record

ReviewLife (Basel, Switzerland)2022

The Protective Role of Neurogenetic Components in Reducing Stress-Related Effects during Spaceflights: Evidence from the Age-Related Positive Memory Approach.

Nicola Mammarella, Matteo Gatti, Irene Ceccato, Adolfo Di Crosta, Alberto Di Domenico, Rocco Palumbo

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Special Issue: 'Advances in Space Biology'.Life (Basel, Switzerland) · 2024
    Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicola MammarellaDepartment of Psychological Sciences, Health and Territory, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
Matteo GattiDepartment of Psychological Sciences, Health and Territory, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-6075-1119
Irene CeccatoDepartment of Neuroscience, Imaging and Clinical Sciences, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0003-4819-2120
Adolfo Di CrostaDepartment of Psychological Sciences, Health and Territory, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-8132-8985
Alberto Di DomenicoDepartment of Psychological Sciences, Health and Territory, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
Rocco PalumboDepartment of Psychological Sciences, Health and Territory, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-2385-5840

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fighting stress-related effects during spaceflight is crucial for a successful mission. Emotional, motivational, and cognitive mechanisms have already been shown to be involved in the decrease of negative emotions. However, emerging evidence is pointing to a neurogenetic profile that may render some individuals more prone than others to focusing on positive information in memory and increasing affective health. The relevance for adaptation to the space environment and the interaction with other stressors such as ionizing radiations is discussed. In particular, to clarify this approach better, we will draw from the psychology and aging literature data. Subsequently, we report on studies on candidate genes for sensitivity to positive memories. We review work on the following candidate genes that may be crucial in adaptation mechanisms: ADRA2B, COMT, 5HTTLPR, CB1, and TOMM40. The final aim is to show how the study of genetics and cell biology of positive memory can help us to reveal the underlying bottom-up pathways to also increasing positive effects during a space mission.

Indexed as

5HTTLPRADRA2BCB1COMTlong-term space missionspositive emotionspositivity effectspaceflightTOMM40

Identifiers

PMID36013355
PMCPMC9410359

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.