ArticleLife (Basel, Switzerland)2022
Ultrasensitive and Selective Detection of Glutathione by Ammonium Carbamate-Gold Platinum Nanoparticles-Based Electrochemical Sensor.
Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- A highly sensitive Au@Pd NRs SERS microarray chip based on electrophoretic deposition for detection of GSH in the serum of colorectal cancer patients.RSC advances · 2026Article
- Biosensing applications of gold-functionalized carbon-based composites.Bioprocess and biosystems engineering · 2026Review
- Copper-doped Lanthanide Coordination Polymers as Luminescent Nanoenzyme for Ratiometric Sensing of HJournal of fluorescence · 2025Article
- Highly selective colorimetric determination of glutathione based on sandwich-structured nanoenzymes composed of gold nanoparticle-coated molecular imprinted metal-organic frameworks.Mikrochimica acta · 2024Article
- Electrochemical investigations and antimicrobial activity of Au nanoparticles photodeposited on titania nanoparticles.Heliyon · 2024Article
- A sensitive electrochemical sensor for glutathione based on specific recognition induced collapse of silver-contained metal organic frameworks.Mikrochimica acta · 2023Article
- Recent Advances in Electrochemical Sensors for Sulfur-Containing Antioxidants.Micromachines · 2023Review
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Authors and funding
7 authors.
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Abstract
Determining the concentration of glutathione is crucial for developing workable medical diagnostic strategies. In this paper, we developed an electrochemical sensor by electrodepositing amino-based reactive groups and gold-platinum nanomaterials on the surface of glassy carbon electrode successively. The sensor was characterized by cyclic voltammetry (CV), field emission scanning electron microscope (FESEM), energy dispersive X-ray spectroscopy (EDX), and electrochemical impedance spectra (EIS). Results showed that Au@Pt nanoparticles with the size of 20-40 nm were presented on the surface of electrode. The sensor exhibits excellent electrocatalytic oxidation towards glutathione. Based on this, we devised an electrochemical biosensor for rapid and sensitive detection of glutathione. After optimizing experimental and operational conditions, a linear response for the concentration of GSH, in the range of 0.1-11 μmol/L, with low detection and quantification limits of 0.051 μM (S/N = 3), were obtained. The sensor also exhibits superior selectivity, reproducibility, low cost, as well as simple preparation and can be applied in human serum sample detection.
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