Evidence map›Paper›PMID 36013241›Full record

ReviewJournal of personalized medicine2022

Pharmacological Efficacy of Probiotics in Respiratory Viral Infections: A Comprehensive Review.

Shadma Wahab, Dalia Almaghaslah, Syed Esam Mahmood, Md Faruque Ahmad, Abdulrahman A Alsayegh, Yahya M Abu Haddash, Mohammad Akhlaquer Rahman, Irfan Ahamd, Wasim Ahmad, Mohammad Khalid and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Review
  3. The Therapeutic Administration ofMicroorganisms · 2026
    Article
  4. Review
  5. Heliyon · 2024
    Review
  6. Article
  7. Microorganisms · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Shadma WahabDepartment of Pharmacognosy, College of Pharmacy, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0001-9941-2918
Dalia AlmaghaslahDepartment of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha 61421, Saudi Arabia.
Syed Esam MahmoodDepartment of Family and Community Medicine, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0001-5264-5677
Md Faruque AhmadDepartment of Clinical Nutrition, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia.
Abdulrahman A AlsayeghDepartment of Clinical Nutrition, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0001-6948-4582
Yahya M Abu HaddashDepartment of Clinical Nutrition, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia.
Mohammad Akhlaquer RahmanDepartment of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, Taif 21974, Saudi Arabia.
Irfan AhamdDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0002-9500-4623
Wasim AhmadDepartment of Pharmacy, Mohammed Al-Mana College for Medical Sciences, Safaa, Dammam 34222, Saudi Arabia.ORCID 0000-0003-2639-9200
Mohammad KhalidDepartment of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj 11942, Saudi Arabia.
Shazia UsmaniHerbal Bioactive Research Laboratory, Faculty of Pharmacy, Integral University, Dasauli, Kursi Road, Lucknow 226026, Uttar Pradesh, India.
Md Parwez AhmadDepartment of Pharmacology, School of Medicine, Maldives National University, Male 20402, Maldives.
Umme HaniDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 61421, Saudi Arabia.
King Khalid University · SAJazan University · SAIntegral University · INMaldives National University · MVPrince Sattam Bin Abdulaziz University · SATaif University · SA

Funding

King Khalid University RGP. 1/ 345/42
6 · The paper itself

Abstract

Mortality and morbidity from influenza and other respiratory viruses are significant causes of concern worldwide. Infections in the respiratory tract are often underappreciated because they tend to be mild and incapacitated. On the other hand, these infections are regarded as a common concern in clinical practice. Antibiotics are used to treat bacterial infections, albeit this is becoming more challenging since many of the more prevalent infection causes have acquired a wide range of antimicrobial resistance. Resistance to frontline treatment medications is constantly rising, necessitating the development of new antiviral agents. Probiotics are one of several medications explored to treat respiratory viral infection (RVI). As a result, certain probiotics effectively prevent gastrointestinal dysbiosis and decrease the likelihood of secondary infections. Various probiotic bacterias and their metabolites have shown immunomodulating and antiviral properties. Unfortunately, the mechanisms by which probiotics are effective in the fight against viral infections are sometimes unclear. This comprehensive review has addressed probiotic strains, dosage regimens, production procedures, delivery systems, and pre-clinical and clinical research. In particular, novel probiotics' fight against RVIs is the impetus for this study. Finally, this review may explore the potential of probiotic bacterias and their metabolites to treat RVIs. It is expected that probiotic-based antiviral research would be benefitted from this review's findings.

Indexed as

immunomodulatory effectsprobioticsprobiotics deliveryrespiratory viral infectionsSARS-CoV-2viral infections

Identifiers

PMID36013241
PMCPMC9409792
OpenAlexW4290599595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.