Evidence map›Paper›PMID 36013046›Full record

ReviewJournal of clinical medicine2022

An Update on the Management of Acute High-Risk Pulmonary Embolism.

Romain Chopard, Julien Behr, Charles Vidoni, Fiona Ecarnot, Nicolas Meneveau

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Romain ChopardDepartment of Cardiology, University Hospital Besançon, 25000 Besancon, France.
Julien BehrDepartment of Radiology, University Hospital Besançon, 25000 Besancon, France.
Charles VidoniDepartment of Cardiology, University Hospital Besançon, 25000 Besancon, France.
Fiona EcarnotDepartment of Cardiology, University Hospital Besançon, 25000 Besancon, France.ORCID 0000-0002-4224-9731
Nicolas MeneveauDepartment of Cardiology, University Hospital Besançon, 25000 Besancon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemodynamic instability and right ventricular (RV) dysfunction are the key determinants of short-term prognosis in patients with acute pulmonary embolism (PE). High-risk PE encompasses a wide spectrum of clinical situations from sustained hypotension to cardiac arrest. Early recognition and treatment tailored to each individual are crucial. Systemic fibrinolysis is the first-line pulmonary reperfusion therapy to rapidly reverse RV overload and hemodynamic collapse, at the cost of a significant rate of bleeding. Catheter-directed pharmacological and mechanical techniques ensure swift recovery of echocardiographic parameters and may possess a better safety profile than systemic thrombolysis. Further clinical studies are mandatory to clarify which pulmonary reperfusion strategy may improve early clinical outcomes and fill existing gaps in the evidence.

Indexed as

catheter-based therapyhigh-risk pulmonary embolismmultidisciplinary care teamsurgical embolectomysystemic thrombolysis

Identifiers

PMID36013046
PMCPMC9409943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.