Evidence map›Paper›PMID 36013036›Full record

ArticleJournal of clinical medicine2022

Is Alcohol Consumption Associated with a Lower Risk of Cardiovascular Events in Patients Treated with Statins? An Observational Real-World Experience.

Jeffrey L Anderson, Viet T Le, Tami L Bair, Joseph B Muhlestein, Kirk U Knowlton, Benjamin D Horne

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jeffrey L AndersonThe Intermountain Medical Center Heart Institute, Salt Lake City, UT 84107, USA.
Viet T LeThe Intermountain Medical Center Heart Institute, Salt Lake City, UT 84107, USA.ORCID 0000-0001-6659-5332
Tami L BairThe Intermountain Medical Center Heart Institute, Salt Lake City, UT 84107, USA.
Joseph B MuhlesteinThe Intermountain Medical Center Heart Institute, Salt Lake City, UT 84107, USA.
Kirk U KnowltonThe Intermountain Medical Center Heart Institute, Salt Lake City, UT 84107, USA.
Benjamin D HorneThe Intermountain Medical Center Heart Institute, Salt Lake City, UT 84107, USA.ORCID 0000-0002-2656-0263
Intermountain Medical Center · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol consumption has long been associated with cardiovascular (CV) benefit, but it also has adverse potential. Statins are currently widely used for CV prevention. We evaluated whether alcohol use is associated with lower CV risk in patients on statins. We searched Intermountain Medical Center cardiac catheterization laboratory medical records for patients with a prescription history of statin use or non-use and a self-report of alcohol use or non-use. Alcohol and statin prescription data were available together with long-term (mean [SD], 4.4 [2.4] years) major adverse CV events (MACE, including death, myocardial infarction, stroke, and heart failure hospitalizations) in 1701 patients at primary and 3266 patients at secondary CV risk. MACE rates were lower for primary prevention alcohol users than non-users not on statins (adjusted hazard ratio [adj-HR] 0.50 (95% CI 0.33, 0.78,

Indexed as

alcoholalcohol consumptioncardiovascular riskstatins

Identifiers

PMID36013036
PMCPMC9410170
OpenAlexW4292259211

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.