Evidence map›Paper›PMID 36013027›Full record

ArticleJournal of clinical medicine2022

Subclinical Myocardial Fibrosis in Systemic Lupus Erythematosus as Assessed by Pulse-Cancellation Echocardiography: A Pilot Study.

Alessandro Giollo, Giulia Vinco, Giovanni Cioffi, Francesca Frizzera, Anna Quinternetto, Corinna Bergamini, Marta Dal Porto, Giovanni Orsolini, Margherita Zen, Andrea Doria and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Alessandro GiolloRheumatology Section, Department of Medicine, University of Verona, 37129 Verona, Italy.ORCID 0000-0001-9355-7673
Giulia VincoDivision of Cardiology, Santa Maria del Carmine Hospital, 38068 Rovereto, Italy.ORCID 0000-0001-7333-427X
Giovanni CioffiRheumatology Section, Department of Medicine, University of Verona, 37129 Verona, Italy.ORCID 0000-0002-2805-9982
Francesca FrizzeraRheumatology Section, Department of Medicine, University of Verona, 37129 Verona, Italy.ORCID 0000-0002-0611-5605
Anna QuinternettoRheumatology Section, Department of Medicine, University of Verona, 37129 Verona, Italy.ORCID 0000-0001-7679-2372
Corinna BergaminiSection of Cardiology, Department of Medicine, University of Verona, 37129 Verona, Italy.
Marta Dal PortoSection of Cardiology, Department of Medicine, University of Verona, 37129 Verona, Italy.
Giovanni OrsoliniRheumatology Section, Department of Medicine, University of Verona, 37129 Verona, Italy.
Margherita ZenRheumatology Section, Department of Medicine, University of Padova, 35128 Padova, Italy.
Andrea DoriaRheumatology Section, Department of Medicine, University of Padova, 35128 Padova, Italy.ORCID 0000-0003-0548-4983
Davide GattiRheumatology Section, Department of Medicine, University of Verona, 37129 Verona, Italy.ORCID 0000-0002-7471-3076
Flavio Luciano RibichiniSection of Cardiology, Department of Medicine, University of Verona, 37129 Verona, Italy.ORCID 0000-0002-6662-0304
Giovanni TargherSection of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Verona, 37129 Verona, Italy.ORCID 0000-0002-4325-3900
Maurizio RossiniRheumatology Section, Department of Medicine, University of Verona, 37129 Verona, Italy.ORCID 0000-0001-9692-2293
Ombretta ViapianaRheumatology Section, Department of Medicine, University of Verona, 37129 Verona, Italy.
University of Verona · ITUniversity of Padua · IT

Funding

Gruppo LES Italia Onlus Aspetti clinici e terapeutici della patologia cardiovascolare in corso di LES (2019)
6 · The paper itself

Abstract

The aim of this study was to examine whether scar imaging echocardiography with ultrasound multi-pulse scheme (eSCAR) can detect subclinical myocardial involvement in systemic lupus erythematosus (SLE). We consecutively recruited SLE patients and controls matched for age, sex, and cardiovascular risk factors. Participants with cardiac symptoms or a prior history of heart disease were excluded. All participants underwent eSCAR and speckle tracking echocardiography (STE) with global longitudinal strain (GLS) assessment. SLE patients were assessed for disease activity and were followed up for 12 months. Myocardial scars by eSCAR were observed in 19% of SLE patients, almost exclusively localized at the inferoseptal myocardial segments, and in none of the controls. GLS was significantly lower in most myocardial segments of SLE patients compared with the controls, especially in the inferoseptal segments. eSCAR-positive SLE patients received a higher cumulative and current dose of prednisone, and had significantly higher levels of anti-dsDNA antibodies (

Indexed as

cardiovascularechocardiographyeSCARflaresglucocorticoidslupusmyocardialmyocarditisstrainultrasound

Identifiers

PMID36013027
PMCPMC9410017
OpenAlexW4292261986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.