Evidence map›Paper›PMID 36013002›Full record

ArticleJournal of clinical medicine2022

Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group.

Valentina Fainardi, Carlo Caffarelli, Michela Deolmi, Kaltra Skenderaj, Aniello Meoli, Riccardo Morini, Barbara Maria Bergamini, Luca Bertelli, Loretta Biserna, Paolo Bottau and 25 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Valentina FainardiPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Carlo CaffarelliPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-7710-6995
Michela DeolmiPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-5877-025X
Kaltra SkenderajPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Aniello MeoliPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0003-3343-4051
Riccardo MoriniPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Barbara Maria BergaminiPaediatric Unit, Department of Medical and Surgical Sciences of Mothers, Children and Adults, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0003-3681-0921
Luca BertelliPediatric Clinic, Scientific Institute for Research and Healthcare (IRCCS) Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Loretta BisernaPaediatrics and Neonatology Unit, Ravenna Hospital, AUSL Romagna, 48121 Ravenna, Italy.
Paolo BottauPaediatrics Unit, Imola Hospital, 40026 Imola, Italy.
Elena CorinaldesiPaediatric Unit, Carpi Hospital, 41012 Carpi, Italy.
Nicoletta De PaulisPaediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.
Arianna DondiPediatric Clinic, Scientific Institute for Research and Healthcare (IRCCS) Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0002-7516-243X
Battista GuidiHospital and Territorial Paediatrics Unit, Pavullo, 41026 Pavullo nel Frignano, Italy.
Francesca LombardiPaediatrics Unit, Maggiore Hospital, 40133 Bologna, Italy.
Maria Sole MagistraliPaediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.
Elisabetta MarastoniPaediatrics Unit, Santa Maria Nuova Hospital, AUSL-IRCCS of Reggio Emilia, 42123 Reggio Emilia, Italy.
Silvia PastorelliPaediatrics Unit, Sassuolo Hospital, 41049 Sassuolo, Italy.
Alessandra PiccorossiPaediatrics and Paediatric Intensive Care Unit, Cesena Hospital, AUSL Romagna, 47521 Cesena, Italy.
Maurizio PoloniPaediatrics Unit, Rimini Hospital, AUSL Romagna, 47921 Rimini, Italy.
Sylvie TagliatiPaediatric Clinic, Ferrara Hospital, 44124 Ferrara, Italy.
Francesca VaientiPaediatrics Unit, G.B. Morgagni-L. Pierantoni Hospital, AUSL Romagna, 47121 Forlì, Italy.
Giuseppe GregoriPrimary Care Pediatricians, AUSL Piacenza, 29121 Piacenza, Italy.ORCID 0000-0003-2803-6518
Roberto SacchettiPrimary Care Pediatricians, AUSL Piacenza, 29121 Piacenza, Italy.
Sandra MariPrimary Care Pediatricians, AUSL Parma, 43126 Parma, Italy.
Manuela MusettiPrimary Care Pediatricians, AUSL Parma, 43126 Parma, Italy.
Francesco AntodaroPrimary Care Pediatricians, AUSL Modena, 41125 Modena, Italy.
Andrea BergomiPrimary Care Pediatricians, AUSL Modena, 41125 Modena, Italy.
Lamberto ReggianiPrimary Care Pediatricians, AUSL Imola, 40026 Imola, Italy.
Fabio CaramelliPediatric Intensive Care Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0003-1759-5664
Alessandro De FantiPaediatrics Unit, Santa Maria Nuova Hospital, AUSL-IRCCS of Reggio Emilia, 42123 Reggio Emilia, Italy.
Federico MarchettiPaediatrics and Neonatology Unit, Ravenna Hospital, AUSL Romagna, 48121 Ravenna, Italy.ORCID 0000-0002-1257-7312
Giampaolo RicciPediatric Clinic, Scientific Institute for Research and Healthcare (IRCCS) Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Susanna EspositoPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Emilia-Romagna Asthma (ERA) Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preschool wheezing should be considered an umbrella term for distinctive diseases with different observable and measurable phenotypes. Despite many efforts, there is a large gap in knowledge regarding management of preschool wheezing. In order to fill this lack of knowledge, the aim of these guidelines was to define management of wheezing disorders in preschool children (aged up to 5 years). A multidisciplinary panel of experts of the Emilia-Romagna Region, Italy, addressed twelve different key questions regarding the management of preschool wheezing. Clinical questions have been formulated by the expert panel using the PICO format (Patients, Intervention, Comparison, Outcomes) and systematic reviews have been conducted on PubMed to answer these specific questions, with the aim of formulating recommendations. The GRADE approach has been used for each selected paper, to assess the quality of the evidence and the degree of recommendations. These guidelines represent, in our opinion, the most complete and up-to-date collection of recommendations on preschool wheezing to guide pediatricians in the management of their patients, standardizing approaches. Undoubtedly, more research is needed to find objective biomarkers and understand underlying mechanisms to assess phenotype and endotype and to personalize targeted treatment.

Indexed as

allergen sensitizationepisodic viral wheezingmultiple trigger wheezingpediatric pulmonologywheezing

Identifiers

PMID36013002
PMCPMC9409690

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.