Evidence map›Paper›PMID 36012956›Full record

ReviewJournal of clinical medicine2022

The Role and Implications of Epicardial Fat in Coronary Atherosclerotic Disease.

Laurentiu Braescu, Marinica Gaspar, Darius Buriman, Oana Maria Aburel, Adrian-Petru Merce, Felix Bratosin, Klokov Sergei Aleksandrovich, Satish Alambaram, Cristian Mornos

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Laurentiu BraescuDepartment of Cardiovascular Surgery, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-1658-7526
Marinica GasparDepartment of Cardiovascular Surgery, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Darius BurimanDepartment of Cardiovascular Surgery, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Oana Maria AburelDepartment of Functional Sciences-Pathophysiology, Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Adrian-Petru MerceDepartment of Cardiovascular Surgery, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Felix BratosinMethodological and Infectious Diseases Research Center, Department of Infectious Diseases, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0003-4711-4315
Klokov Sergei AleksandrovichNV Sklifosovsky Research Institute for Emergency Medicine, Bolshaya Sukharevskaya Ploshchad 3, 129090 Moscow, Russia.
Satish AlambaramBhaskar Medical College, Amdapur Road 156-162, Hyderabad 500075, India.
Cristian MornosDiscipline of Cardiology, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROGandhi Medical College & Hospital · INResearch Institute of Emergency Care · RU

Funding

Victor Babeș University of Medicine and Pharmacy Timișoara MITO-MB-CURAT:2POSTDOC/1387/03.02.2020
6 · The paper itself

Abstract

The current minireview aims to assess the implications of epicardial fat secretory function in the development of coronary artery disease. The epicardial adipose tissue (EAT) is a visceral fat depot that has been described as a cardiovascular risk factor. In addition to its mechanical protection role and physiological secretory function, it seems that various secretion products of the epicardial fat are responsible for metabolic disturbances at the level of the cardiac muscle when in association with pre-existing pathological conditions, such as metabolic syndrome. There is a pathological reduction in sarcomere shortening, abnormal cytosolic Ca

Indexed as

atherosclerosiscoronary artery diseaseepicardial fatmetabolic syndromeoxidative stress

Identifiers

PMID36012956
PMCPMC9410442
OpenAlexW4291465165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.